ArticleAnnals of medicine and surgery (2012)2021
Correlation of inflammatory cytokines on corrected QT interval in rifampicin-resistant tuberculosis patients.
Article in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Dynamic evaluation of serum atherogenic factors as a predictor of QT interval prolongation in patients with type 2 diabetes mellitus.American journal of translational research · 2026Article
- Interstitial lung disease in Indonesian adult with systemic sclerotic: A rare case.Annals of medicine and surgery (2012) · 2022Article
- Disseminated tuberculosis with symptoms of decreased consciousness: A rare case in Indonesian male.Annals of medicine and surgery (2012) · 2022Article
- The role of C-Reactive protein as an inflammatory marker to predict prolonged QTc interval in rifampicin-resistant tuberculosis patients: A case-control study.Annals of medicine and surgery (2012) · 2021Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe cases of Rifampicin-Resistant Tuberculosis (RR-TB) in our country have increased every year and RR-TB deaths are thought to be caused by prolongation of the QTc interval due to side effects of anti-tuberculosis drugs. Thus, cytokines are needed to be used as early markers of prolongation of the QTc interval in RR-TB patients.
objectiveThis study aims to analyze the correlation of inflammatory cytokines on QTc interval in RR-TB patients who received shorter regimens.
methodsThis study uses a case-control study with a time series conducted in the period September 2019 to February 2020 in one of the referral hospitals for Tuberculosis in Indonesia. Cytokines levels from blood samples were measured using the ELISA method, while QTc intervals were automatically recorded using an electrocardiography machine. The statistical analysis used was the Chi-square test, Man Whitney test, Independence
resultsThere was no significant correlation between inflammatory cytokines and QTc prolongation in intensive phase which TNF-α value (6.8 pg/ml;
conclusioninflammatory cytokines (TNF-α, IL-1β, and IL-6) cannot be used to identify QTc interval prolongation in RR-TB patients who received shorter regimens.
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