ArticleDental research journal2021
The effect of Vitamin E supplementation on treatment of chronic periodontitis.
Article in Dental research journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Oxidative stress and antioxidant pathways in the pathogenesis of periodontitis and peri-implantitis: mechanistic insights and therapeutic potentials.Frontiers in oral health · 2026Review
- Vitamins in the Treatment of Periodontitis: Molecular Mechanism and Network Pharmacological Analysis.Oral health & preventive dentistry · 2025Review
- Effect of Nutritional Antioxidants on Periodontal Disease and Periodontal Therapy.Dentistry journal · 2025Review
- Serum levels of vitamin E, vitamin D, and omega-3 fatty acids in patients with generalized chronic periodontitis: A cross-sectional study.Journal of dental research, dental clinics, dental prospects · 2025Article
- Association between composite dietary antioxidant index and the prevalence of periodontitis: results from NHANES 2009-2014.BMC oral health · 2025Article
- Impact of Tocopherol Supplementation on Clinical Parameters of Periodontal Disease: A Systematic Review and Meta-Analysis.Journal of personalized medicine · 2024Review
- Evaluating the Protective Role of Vitamin A Supplementation in Periodontal Health: A Comprehensive Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Nutritional Deficiencies and Associated Oral Health in Adolescents: A Comprehensive Scoping Review.Children (Basel, Switzerland) · 2024Article
- Review
- The Emerging Role of Salivary Oxidative Stress Biomarkers as Prognostic Markers of Periodontitis: New Insights for a Personalized Approach in Dentistry.Journal of personalized medicine · 2023Review
- Global trends in research on oxidative stress associated with periodontitis from 1987 to 2022: A bibliometric analysis.Frontiers in immunology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to evaluate the effect of Vitamin E supplements on chronic periodontitis based on the clinical parameters of pocket depth and clinical attachment level and total antioxidant capacity (TAC) of saliva. MATERIALS AND
methodsIn this clinical trial, 16 patients with chronic periodontitis were selected and divided into two groups. The indices of pocket depth and attachment loss for 6 teeth per person were measured with a periodontal probe. A total of 41 teeth in the control group and 42 teeth in the case group were examined. Then, 2 ml nonstimulated saliva was collected from each patient. All patients were treated with scaling and root planing (SRP). The case group consumed 200 IU supplementary Vitamin E daily for up to 2 months. After 2 months, clinical indices were re-measured and 2 ml nonstimulated saliva was collected. The TAC of saliva samples was measured by using Zellbio's TAC Kit. Data were analyzed by the SPSS software and were evaluated in each group between the first session and 2 months later with paired
resultsIndependent
conclusionThe results of this study indicate that Vitamin E supplementation with SRP can reduce the inflammatory process of periodontitis and improve periodontal clinical indices and decrease the amount of attachment loss.
Indexed as
Identifiers
34584640PMC8428286W3193403171What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.