ReviewComputational and structural biotechnology journal2021
Modelling microbial communities: Harnessing consortia for biotechnological applications.
Review in Computational and structural biotechnology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Systems engineering of engineered live biotherapeutics: A discovery-to-translation framework for streamlining microbiome therapeutic development.Journal of controlled release : official journal of the Controlled Release Society · 2026Review
- Article
- Synthetic microbial communities: from theoretical exploration to applied innovation.World journal of microbiology & biotechnology · 2026Review
- Bacterial consortium construction for inhibition ofFrontiers in microbiology · 2026Review
- Harnessing Microbial Consortia for Efficient Keratinous Biomass Biotransformation.International journal of molecular sciences · 2025Review
- Recent trends in microbial production of alkanes.World journal of microbiology & biotechnology · 2025Review
- COmmunity and Single Microbe Optimisation System (COSMOS).NPJ systems biology and applications · 2025Article
- Article
- Genome-Scale Community Model-Guided Development of Bacterial Coculture for Lignocellulose Bioconversion.Biotechnology and bioengineering · 2025Article
- Strain identity effects contribute more to Pseudomonas community functioning than strain interactions.The ISME journal · 2025Article
- Construction of a syntrophicSynthetic biology (Oxford, England) · 2025Article
- Strategies and tools to construct stable and efficient artificial coculture systems as biosynthetic platforms for biomass conversion.Biotechnology for biofuels and bioproducts · 2024Review
- Deciphering and designing microbial communities by genome-scale metabolic modelling.Computational and structural biotechnology journal · 2024Review
- The repertoire and levels of secondary metabolites in microbial cocultures depend on the inoculation ratio: a case study involving Aspergillus terreus and Streptomyces rimosus.Biotechnology letters · 2024Article
- Panera: An innovative framework for surmounting uncertainty in microbial community modeling using pan-genera metabolic models.iScience · 2024Article
- Integration of metataxonomic data sets into microbial association networks highlights shared bacterial community dynamics in fermented vegetables.Microbiology spectrum · 2024Article
- Designing function-specific minimal microbiomes from large microbial communities.NPJ systems biology and applications · 2024Article
- PyCoMo: a python package for community metabolic model creation and analysis.Bioinformatics (Oxford, England) · 2024Article
- Top-down and bottom-up microbiome engineering approaches to enable biomanufacturing from waste biomass.Journal of industrial microbiology & biotechnology · 2024Review
- Strategies for tailoring functional microbial synthetic communities.The ISME journal · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microbes propagate and thrive in complex communities, and there are many benefits to studying and engineering microbial communities instead of single strains. Microbial communities are being increasingly leveraged in biotechnological applications, as they present significant advantages such as the division of labour and improved substrate utilisation. Nevertheless, they also present some interesting challenges to surmount for the design of efficient biotechnological processes. In this review, we discuss key principles of microbial interactions, followed by a deep dive into genome-scale metabolic models, focussing on a vast repertoire of constraint-based modelling methods that enable us to characterise and understand the metabolic capabilities of microbial communities. Complementary approaches to model microbial communities, such as those based on graph theory, are also briefly discussed. Taken together, these methods provide rich insights into the interactions between microbes and how they influence microbial community productivity. We finally overview approaches that allow us to generate and test numerous synthetic community compositions, followed by tools and methodologies that can predict effective genetic interventions to further improve the productivity of communities. With impending advancements in high-throughput omics of microbial communities, the stage is set for the rapid expansion of microbial community engineering, with a significant impact on biotechnological processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.