Evidence map›Paper›PMID 34584587›Full record

ArticlePrzeglad gastroenterologiczny2021

Clinical importance of serum CEA and CA-19-9 levels in oesophagogastric junction adenocarcinomas.

Ozlem Zeliha Sert, Hilmi Bozkurt, Tolga Olmez, Emre Aray, Orhan Uzun, Selcuk Gulmez, Aziz Serkan Senger, Mustafa Duman, Erdal Polat

Open access · goldAbstract read
In one paragraph

Article in Przeglad gastroenterologiczny, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ozlem Zeliha SertDepartment of General Surgery, University of Health Sciences, Haydarpasa Education and Research Hospital, Istanbul, Turkey.
Hilmi BozkurtDepartment of General Surgery, University of Health Sciences, Haseki Education and Research Hospital, Istanbul, Turkey.
Tolga OlmezDepartment of Gastrointestinal Surgery, University of Health Sciences, Adana City Education and Research Hospital, Adana, Turkey.
Emre ArayDepartment of General Surgery, University of Health Sciences, Kutahya Evliya Celebi High Education and Research Hospital, Kutahya, Turkey.
Orhan UzunDepartment of Gastrointestinal Surgery, University of Health Sciences, Kartal Kosuyolu High Education and Research Hospital, Istanbul, Turkey.
Selcuk GulmezDepartment of Gastrointestinal Surgery, University of Health Sciences, Kartal Kosuyolu High Education and Research Hospital, Istanbul, Turkey.
Aziz Serkan SengerDepartment of Gastrointestinal Surgery, University of Health Sciences, Kartal Kosuyolu High Education and Research Hospital, Istanbul, Turkey.
Mustafa DumanDepartment of Gastrointestinal Surgery, University of Health Sciences, Kartal Kosuyolu High Education and Research Hospital, Istanbul, Turkey.
Erdal PolatDepartment of Gastrointestinal Surgery, University of Health Sciences, Kartal Kosuyolu High Education and Research Hospital, Istanbul, Turkey.
Sağlık Bilimleri Üniversitesi · TRHaseki Eğitim ve Araştırma Hastanesi · TRHaydarpaşa Numune Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn recent years, the incidence of gastroesophageal junction tumors has increased rapidly in worldwide.

aimTo evaluate pretreatment serum carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 19-9 in oesophagogastric junction (OGJ) adenocarcinomas regarding clinicopathologic characteristics and overall survival. MATERIAL AND

methodsPatients undergoing curative surgery diagnosed with OGJ adenocarcinoma in the gastrointestinal surgery clinic between 2007 and 2019 were included in the study retrospectively. Kaplan Meier and Log Rank tests were performed in survival analyses. Logistic regression analysis was performed to state the independent variables affecting survival.

resultsThe mean age of the 70 patients included in the study was 59.78 ±10.49 (31-76) years. Serum CEA and CA 19-9 were high in 19 (27.1%) patients. CEA ≥ 5 ng/ml was found to be statistically significant in patients receiving neoadjuvant chemotherapy (NAC) and in patients with a high number of positive lymph nodes (N +) (

conclusionsIn our study, a significant relationship was found in terms of overall survival and serum CA 19-9 in OGJ adenocarcinoma, and it was associated with both tumour markers being positive and the mean N+ value.

Indexed as

adenocarcinomaoesophagogastric junctionprognosissurvivaltumour markers

Identifiers

PMID34584587
PMCPMC8456764
OpenAlexW3204186214

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.