Evidence map›Paper›PMID 34584413›Full record

ArticleNeuropsychiatric disease and treatment2021

Severity of Depressive Symptoms is Associated with Venous Thromboembolism in Hospitalized Patients with a Major Depressive Episode.

Kazuhisa Yoshizawa, Masahiro Takeshima, Sayaka Ishino, Masaya Ogasawara, Dai Fujiwara, Yu Itoh, Aya Imanishi, Hidenobu Ohta, Kazuo Mishima

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kazuhisa YoshizawaDepartment of Psychiatry, Akita Prefectural Center for Rehabilitation and Psychiatric Medicine, Daisen City, Akita, 019-2492, Japan.ORCID 0000-0003-0600-4515
Masahiro TakeshimaDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita City, Akita, 010-8543, Japan.ORCID 0000-0003-0614-7524
Sayaka IshinoDepartment of Neuropsychiatry, Sugawara Hospital, Yurihonjo City, Akita, 015-0012, Japan.
Masaya OgasawaraDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita City, Akita, 010-8543, Japan.
Dai FujiwaraDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita City, Akita, 010-8543, Japan.
Yu ItohDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita City, Akita, 010-8543, Japan.ORCID 0000-0002-8384-8554
Aya ImanishiDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita City, Akita, 010-8543, Japan.
Hidenobu OhtaDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita City, Akita, 010-8543, Japan.
Kazuo MishimaDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita City, Akita, 010-8543, Japan.ORCID 0000-0003-1182-1181
Akita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA major depressive episode is a risk factor for venous thromboembolism (VTE) in psychiatric inpatients. However, it is unclear whether the severity of depressive symptoms or duration of the current depressive episode is associated with VTE. Further, the VTE prevalence among hospitalized patients with a major depressive episode receiving electroconvulsive therapy is unknown. This retrospective study examined factors associated with VTE among hospitalized patients with a major depressive episode and estimated the prevalence of VTE in such patients who underwent electroconvulsive therapy. PATIENTS AND

methodsPatients with a major depressive episode hospitalized in the Department of Neuropsychiatry at Akita University Hospital between January 2018 and December 2020 were included. Data from the first week of hospitalization were extracted from medical records. VTE was diagnosed based on the findings of computed tomography. To evaluate whether the severity of depressive symptoms or duration of the current depressive episode was associated with VTE, logistic regression analysis was conducted after adjusting for covariates with known VTE risk factors (antidepressants, antipsychotics, and physical comorbidities).

resultsWe analyzed 133 patients; of these, 14 were diagnosed with asymptomatic VTE. The severity of depressive symptoms (odds ratio: 1.220, 95% confidence interval: 1.081-1.377, p = 0.001) was significantly associated with VTE. The prevalence of VTE among those receiving electroconvulsive therapy was 35% (7/20).

conclusionThe prevalence of VTE was 35% among patients receiving in-hospital electroconvulsive therapy for a major depressive episode. VTE should be considered for hospitalized patients with severe depressive symptoms and patients receiving in-hospital electroconvulsive therapy for a major depressive episode.

Indexed as

bipolar depressiondepressive symptomselectroconvulsive therapyunipolar depressionvenous thromboembolism

Identifiers

PMID34584413
PMCPMC8464371
OpenAlexW3201425212

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.