ReviewInternational journal of nanomedicine2021
Nanomaterials-Upconverted Hydroxyapatite for Bone Tissue Engineering and a Platform for Drug Delivery.
Review in International journal of nanomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 127 citations in OpenAlex.
- A novel multifunctional split-type porous biomimetic absorbable mPLA-HA lamina for spinal posterior column reconstruction following laminectomy.Bioactive materials · 2026Article
- Organ-on-chip (OoC) and nano-biomaterials: next generation of precision oral and dental healthcare research.Journal of nanobiotechnology · 2026Review
- Synergistic integration of biomaterials in orthopedic implantation for infection preventing and tissue engineering.Regenerative biomaterials · 2026Review
- Current state of bioceramic bone repair materials in immune regulation: a review.Frontiers of medicine · 2025Review
- Extraction and Characterization of Aceh Bovine Bone-Derived Hydroxyapatite for Applications in Dentistry.European journal of dentistry · 2025Article
- In Situ Preparation of Composite Scaffolds Based on Polyurethane and Hydroxyapatite Particles for Bone Tissue Engineering.ACS omega · 2025Article
- Regulation of Bone Remodeling by Metal-Phenolic Networks for the Treatment of Systemic Osteoporosis.ACS applied materials & interfaces · 2025Article
- 3D scaffold of hydroxyapatite/β tricalcium phosphate from mussel shells: Synthesis, characterization and cytotoxicity.Heliyon · 2025Article
- Fabrication of biocidal materials based on the molecular interactions of tetracycline and quercetin with hydroxyapatite viaHeliyon · 2025Article
- Applications of Hydroxyapatite-Based Polymeric Scaffolds in Bone Tissue Engineering: An Update.Advanced pharmaceutical bulletin · 2024Review
- Design andNanomedicine (London, England) · 2024Article
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- Magnetic Hydroxyapatite Nanoparticles in Regenerative Medicine and Nanomedicine.International journal of molecular sciences · 2024Review
- 3D bioprinting technology to construct bone reconstruction research model and its feasibility evaluation.Frontiers in bioengineering and biotechnology · 2024Article
- Synthesis and Characterization of Epigallocatechin Gallate-mediated Hydroxyapatite.Pharmaceutical nanotechnology · 2024Article
- Cheminformatics-Based Design and Synthesis of Hydroxyapatite/Collagen Nanocomposites for Biomedical Applications.Polymers · 2023Article
- Cryogel Scaffolds for Tissue-Engineering: Advances and Challenges for Effective Bone and Cartilage Regeneration.Gels (Basel, Switzerland) · 2023Review
- Hydroxyapatite Incorporated with FeACS omega · 2023Article
- Materials in the NaMaterials (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydroxyapatite is a basic mineral that is very important to the human body framework. Recently, synthetic hydroxyapatite (SHA) and its nanocomposites (HANs) are the subject of intense research for bone tissue engineering and drug loading system applications, due to their unique, tailor-made characteristics, as well as their similarities with the bone mineral component in the human body. Although hydroxyapatite has good biocompatibility and osteoconductive characteristics, the poor mechanical strength restricts its use in non-load-bearing applications. Consequently, a rapid increase in reinforcing of other nanomaterials into hydroxyapatite for the formation of HANs could improve the mechanical properties. Most of the research reported on the success of other nanomaterials such as metals, ceramics and natural/synthetic polymers as additions into hydroxyapatite is reviewed. In addition, this review also focuses on the addition of various substances into hydroxyapatite for the formation of various HANs and at the same time to try to minimize the limitations so that various bone tissue engineering and drug loading system applications can be exploited.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.