Evidence map›Paper›PMID 34584375›Full record

ArticleChinese journal of cancer research = Chung-kuo yen cheng yen chiu2021

Features of colorectal cancer in China stratified by anatomic sites: A hospital-based study conducted in university-affiliated hospitals from 2014 to 2018.

Ruize Qu, Yanpeng Ma, Liyuan Tao, Xiaoyuan Bao, Xin Zhou, Bingyan Wang, Fei Li, Siyi Lu, Lin Tuo, Siyan Zhan and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Observational
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  6. Postoperative chemoradiotherapy with capecitabine and oxaliplatinChinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Ruize QuDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Yanpeng MaDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Liyuan TaoClinical Epidemiology Research Center, Peking University Third Hospital, Beijing 100191, China.
Xiaoyuan BaoMedical Information Center, Peking University Health Science Center, Beijing 100191, China.
Xin ZhouDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Bingyan WangDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Fei LiDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Siyi LuDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Lin TuoDepartment of Hospital Management, Peking University Health Science Center, Beijing 100191, China.
Siyan ZhanClinical Epidemiology Research Center, Peking University Third Hospital, Beijing 100191, China.
Zhipeng ZhangDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Wei FuDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.
Peking University · CNPeking University Third Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe clinical and biological characteristics of colorectal cancer have been found to differ depending on the anatomic site of the cancer. However, for Chinese patients, there is limited information on the proportion of cases at each site and the related features. In this study, we explored the location, distribution and other features of colorectal cancers at each anatomic site in Chinese patients.

methodsWe conducted a hospital-based study using hospitalization summary reports from 10 Peking University-affiliated hospitals from 2014 to 2018; the reports covered a total of 2,097,347 hospitalizations. Incident cases were chosen as the study population, and their epidemiological features were further analyzed.

resultsA total of 20,739 colorectal cancer patients were identified. Rectum was the most common location (48.3%) of the cancer, whereas the proportions of patients with distal and proximal colon cancer were 24.5% and 18.6%, respectively. Patients with rectal cancer were predominantly male and were the youngest for all anatomical sites (each P<0.001). The highest proportion of emergency admissions, the longest hospital stays and the highest hospitalization costs were found in patients with proximal colon cancer (each P<0.001). The proximal colon cancer subgroup included the highest proportions of patients with medical histories of cholecystectomy, cholecystolithiasis and/or gallbladder polyps and appendectomy (P=0.009, P<0.001 and P<0.001, respectively). The distal colon cancer subgroup included the highest proportions of patients with medical histories of diabetes and hypertension (P<0.001, respectively).

conclusionsThe patterns of colorectal cancer observed in this study differ from those reported for Western patients and show a significantly higher proportion of patients with rectal cancer. Different epidemiological features were also found based on anatomic sites. Further studies based on tumor location should be conducted to facilitate more accurate screening and treatment.

Indexed as

Anatomic sitecolorectal cancerdatabasehospitalization

Identifiers

PMID34584375
PMCPMC8435820
OpenAlexW3199804564

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.