Evidence map›Paper›PMID 34584313›Full record

ArticleIndian journal of psychological medicine2021

The Limitations of Quasi-Experimental Studies, and Methods for Data Analysis When a Quasi-Experimental Research Design Is Unavoidable.

Chittaranjan Andrade

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of psychological medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Review
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  14. Article
  15. Conducting and Writing Quantitative and Qualitative Research.Journal of Korean medical science · 2023
    Review
  16. Article
  17. Research Design: Case-Control Studies.Indian journal of psychological medicine · 2022
    Article
  18. Article
  19. Research Design: Cohort Studies.Indian journal of psychological medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Chittaranjan AndradeDept. of Clinical Psychopharmacology and Neurotoxicology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.ORCID https://orcid.org/0000-0003-1526-567X
National Institute of Mental Health and Neurosciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A quasi-experimental (QE) study is one that compares outcomes between intervention groups where, for reasons related to ethics or feasibility, participants are not randomized to their respective interventions; an example is the historical comparison of pregnancy outcomes in women who did versus did not receive antidepressant medication during pregnancy. QE designs are sometimes used in noninterventional research, as well; an example is the comparison of neuropsychological test performance between first degree relatives of schizophrenia patients and healthy controls. In QE studies, groups may differ systematically in several ways at baseline, itself; when these differences influence the outcome of interest, comparing outcomes between groups using univariable methods can generate misleading results. Multivariable regression is therefore suggested as a better approach to data analysis; because the effects of confounding variables can be adjusted for in multivariable regression, the unique effect of the grouping variable can be better understood. However, although multivariable regression is better than univariable analyses, there are inevitably inadequately measured, unmeasured, and unknown confounds that may limit the validity of the conclusions drawn. Investigators should therefore employ QE designs sparingly, and only if no other option is available to answer an important research question.

Indexed as

confounding variablesmultivariable regressionQuasi-experimental studyresearch designunivariable analysis

Identifiers

PMID34584313
PMCPMC8450731
OpenAlexW3193908531

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.