Evidence map›Paper›PMID 34584188›Full record

ArticleScientific reports2021

Receptor tyrosine kinase ROR1 ameliorates Aβ

Kaushik Chanda, Nihar Ranjan Jana, Debashis Mukhopadhyay

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  8. Plasma proteomic analysis identifies proteins and pathways related to Alzheimer's risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  9. Review
  10. The impact of ERCell death & disease · 2025
    Article
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  17. The lncRNAbioRxiv : the preprint server for biology · 2023
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kaushik ChandaBiophysics and Structural Genomics Division, Saha Institute of Nuclear Physics, HBNI, Block-AF, Sector 1, Bidhannagar, Kolkata, WB, 700 064, India.ORCID 0000-0002-8600-5210
Nihar Ranjan JanaCellular and Molecular Neuroscience Laboratory, National Brain Research Centre, Manesar, Gurgaon, 122 050, India.
Debashis MukhopadhyayBiophysics and Structural Genomics Division, Saha Institute of Nuclear Physics, HBNI, Block-AF, Sector 1, Bidhannagar, Kolkata, WB, 700 064, India. debashis.mukhopadhyay@saha.ac.in.ORCID 0000-0002-4516-2260
Saha Institute of Nuclear Physics · INIndian Institute of Technology Kharagpur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) involves severe cytoskeletal degradation and microtubule disruption. Here, we studied the altered dynamics of ROR1, a Receptor Tyrosine Kinase (RTK), and how it could counter these abnormalities. We found that in an Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAnimalsCell Line, TumorDisease Models, AnimalHumansMiceMicroRNAsPeptide FragmentsPresenilin-1ProteolysisReceptor Tyrosine Kinase-like Orphan ReceptorsRNA, Long NoncodingAmyloid beta-Peptidesamyloid beta-protein (1-42)Amyloid beta-Protein PrecursorAPP protein, humanMicroRNAsMIRN146 microRNA, humanMirn146 microRNA, mouseMIRN34a microRNA, mouseMIRN34 microRNA, humanNEAT1 long non-coding RNA, humanNEAT1 long non-coding RNA, mousePeptide FragmentsPresenilin-1PSEN1 protein, humanReceptor Tyrosine Kinase-like Orphan ReceptorsRNA, Long NoncodingROR1 protein, humanRor1 protein, mouse

Identifiers

PMID34584188
PMCPMC8479066
OpenAlexW3203778170

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.