ArticleScientific reports2021
Real-world effectiveness of hyperbaric oxygen therapy for delayed neuropsychiatric sequelae after carbon monoxide poisoning.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 22 citations in OpenAlex.
- Study on the construction of a predictive model for delayed encephalopathy after acute carbon monoxide poisoning.BMC neurology · 2026Article
- Optimizing hyperbaric oxygen initiation time in carbon monoxide poisoning: a 3-hour window enhances neurological recovery via lactate clearance.Open medicine (Warsaw, Poland) · 2026Article
- Core Neuroinflammatory Pathways Contributing to Delayed Encephalopathy After Acute Carbon Monoxide Poisoning Revealed by Multi-omics and Single Nucleus RNA-Seq.Current medicinal chemistry · 2026Article
- Delayed Postanoxic Encephalopathy Following Acute Carbon Monoxide Poisoning: A Case Report and Literature Review.Cureus · 2025Article
- Trend analysis and prediction of disease burden of occupational carbon monoxide poisoning in China based on the past two decades.Scientific reports · 2025Article
- Cortical microstructural change linked to clinical recovery in subacute delayed encephalopathy after acute carbon monoxide poisoning: a longitudinal case report.Frontiers in toxicology · 2025Article
- Early and late adverse clinical outcomes of severe carbon monoxide intoxication: A cross-sectional retrospective study.PloS one · 2024Article
- Delayed neuropsychiatric sequelae with improvement of decreased cerebral bold flow by single-photon emission computed tomography during hyperbaric oxygen therapy: A case report with a 10-year follow-up.PCN reports : psychiatry and clinical neurosciences · 2023Article
- Effectiveness of Initial Troponin I and Brain Natriuretic Peptide Levels as Biomarkers for Predicting Delayed Neuropsychiatric Sequelae in Patients with CO Poisoning: A Retrospective Multicenter Observational Study.Journal of personalized medicine · 2023Article
- Establishment and application of severity assessment system for patients with delayed encephalopathy caused by carbon monoxide poisoning.American journal of translational research · 2023Article
- Multi-Modal Synergistic 99mTc-TRODAT-1 SPECT and MRI for Evaluation of the Efficacy of Hyperbaric Oxygen Therapy in CO-Induced Delayed Parkinsonian and Non-Parkinsonian Syndromes.Antioxidants (Basel, Switzerland) · 2022Article
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Authors and funding
4 authors at 4 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
To assess real-world effectiveness of hyperbaric oxygen therapy (HBOT) on delayed neuropsychiatric sequelae (DNS) after carbon monoxide (CO) poisoning we conducted a retrospective review of patients with CO poisoning admitted to Linkou Chang-Gung Memorial Hospital, Taiwan's largest medical center, during 2009-2015. We included patients developing DNS after CO poisoning and compared improvements in neuropsychiatric function, with and without HBOT, after 12 months post-DNS to understand differences in recovery rates. DNS improvement-associated factors were also evaluated. We used receiver operating characteristic (ROC) curve analysis to assess the role of time elapsed between DNS diagnosis and HBOT initiation in predicting DNS improvement. A total of 62 patients developed DNS, of whom 11 recovered while the rest did not. Possible factors predicting DNS improvement included receiving HBOT post-DNS (72.7% vs 25.5%; P = 0.006), and treatment with more than three HBOT sessions during acute stage CO poisoning (81.8% vs 27.5%; P = 0.003). The relevant area under the ROC curve was 0.789 (95% CI 0.603-0.974), and the best cut-off point was 3 days post-DNS diagnosis, with 87.5% sensitivity and 61.5% specificity. Early HBOT in patients who developed DNS after CO poisoning significantly improved their DNS symptoms, with treatment effects sustained for 1 year after DNS diagnosis.
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