Evidence map›Paper›PMID 34583983›Full record

ArticleOpen heart2021

Ventricular-vascular coupling is predictive of adverse clinical outcome in paediatric pulmonary arterial hypertension.

Melanie J Dufva, Dunbar Ivy, Kristen Campbell, Aimee Lam, Adam Rauff, Karel T N Breeman, Johannes M Douwes, Rolf M F Berger, Vitaly Oleg Kheyfets, Kendall Hunter

Open access · goldAbstract read
In one paragraph

Article in Open heart, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Melanie J DufvaBioengineering, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA melanie.dufva@cuanschutz.edu.ORCID 0000-0002-2920-3464
Dunbar IvyCardiology, Children's Hospital Colorado, Aurora, Colorado, USA.
Kristen CampbellCardiology, Children's Hospital Colorado, Aurora, Colorado, USA.
Aimee LamBioengineering, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA.
Adam RauffBioengineering, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA.
Karel T N BreemanCardiology, Children's Hospital Colorado, Aurora, Colorado, USA.
Johannes M DouwesPaediatric Cardiology, University Medical Center Groningen Department of Cardiology, Groningen, The Netherlands.
Rolf M F BergerPaediatric Cardiology, University Medical Center Groningen Department of Cardiology, Groningen, The Netherlands.
Vitaly Oleg KheyfetsBioengineering, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA.
Kendall HunterBioengineering, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA.
Children's Hospital Colorado · USUniversity Medical Center Groningen · NLUniversity of Utah · US

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Inter-ventricular decoupling is an overlooked contributor to right ventricular myocardial stress and dysfunction in pediatric pulmonary hypertensionK25HL133481 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI KHEYFETS, VITALY · 2017 to 2021
$605k
NCATS NIH HHS UL1 TR002535NHLBI NIH HHS K25 HL133481
6 · The paper itself

Abstract

aimsVentricular-vascular coupling, the ratio between the right ventricle's contractile state (E

methodsOne hundred and thirty paediatric patients who were diagnosed with PAH via right heart catheterisation were retrospectively reviewed over a 10-year period. Maximum RV isovolumic pressure and end-systolic pressure were estimated using two single-beat methods from Takeuchi

resultsIn patients with IPAH/HPAH, E

conclusionsE

Indexed as

ForecastingAdolescentBlood PressureCardiac CatheterizationChildFemaleFollow-Up StudiesHeart VentriclesHumansInfantMalePulmonary Arterial HypertensionPulmonary ArteryRetrospective StudiesStroke VolumeVentricular Function, Righthealthcarehypertensionoutcome assessmentpulmonarypulmonary arterial hypertension

Identifiers

PMID34583983
PMCPMC8479945
OpenAlexW3203667516

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.