ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2022
The rewarding effects of alcohol after bariatric surgery: do they change and are they associated with pharmacokinetic changes?
Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Alcohol Misuse post Metabolic and Bariatric Surgery: A Systematic Review of Longer-term Studies with Focus on new Onset Alcohol use Disorder and Differences Between Surgery Types.Current obesity reports · 2024Pooled it
- A Technology-Based Intervention to Reduce Alcohol Use After Metabolic and Bariatric Surgery: Examination of Six-month Follow-up Outcomes Following a Pilot Randomized Controlled Trial.Obesity surgery · 2026Trial
- Postoperative factors associated with hazardous alcohol use after metabolic and bariatric surgery.Surgical endoscopy · 2026Article
- Alcohol and Substance Use After Bariatric Surgery: Nutritional Risks and Clinical Implications in Long-Term Postoperative Care.Nutrients · 2026Review
- Increased alcohol intake and alcohol use disorder following bariatric surgery: potential mechanisms.Physiology & behavior · 2025Review
- The Nutritional Condition of Individuals With Alcohol Use Disorder Following Bariatric Surgery: A Systematic Review.Cureus · 2025Review
- Alcohol use disorder and alcohol-related mortality after metabolic bariatric surgery: prospective controlled cohort study.The British journal of surgery · 2025Article
- ALCOHOL USE DISORDER AND DEPRESSION IN PATIENTS AFTER UNDERGOING BARIATRIC SURGERY.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2025Article
- Glucagon-like peptide-1, fibroblast growth factor 21, and other endocrine responses to alcohol ingestion in women before and after metabolic surgery.Frontiers in pharmacology · 2025Article
- Article
- Alcohol associated liver disease and bariatric surgery: Current perspectives and future directions.World journal of gastrointestinal surgery · 2024Review
- Incidence of adverse mental health outcomes after sleeve gastrectomy compared with gastric bypass and restrictive bariatric procedures: a retrospective cohort study.Obesity (Silver Spring, Md.) · 2023Article
- Deficits in cognitive control during alcohol consumption after bariatric surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundResearch shows that surgery patients who have undergone Roux-en-Y gastric bypass (RYGB) are at increased risk for an alcohol use disorder (AUD). However, the mechanisms through which this increased risk is incurred are poorly understood. A host of variables have been proposed as potentially causal in developing AUDs, but empirical examination of many of these variables in human samples is lacking.
objectivesOur objective was to examine the extent to which alcohol pharmacokinetics (PK), the rewarding effects of alcohol, and the relationship between these variables change from before to after weight loss surgery.
settingLarge healthcare facility in the Midwest United States
methodsThirty-four participants completed assessments before and 1 year after RYGB. They completed laboratory sessions and provided data on the PK of alcohol and the extent to which alcohol was reinforcing to them at each timepoint.
resultsFindings show that the PK effects of alcohol (P < .01) and how rewarding alcohol was reported to be (P < .01) changed from before to 1 year after weight loss surgery. Further, statistically significant increases in the association between these variables were witnessed from before to 1 year after surgery (P < .01).
conclusionThese results implicate changes (from before surgery to one year after) in the reinforcing and PK effects of alcohol as possible mechanisms for increased risk of alcohol use disorder following Roux-en-Y gastric bypass surgery.
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