Evidence map›Paper›PMID 34583642›Full record

ArticleBMC medical imaging2021

Differentiating T1a-T1b from T2 in gastric cancer lesions with three different measurement approaches based on contrast-enhanced T1W imaging at 3.0 T.

Yuan Yuan, Shengnan Ren, Tiegong Wang, Fu Shen, Qiang Hao, Jianping Lu

Open access · goldAbstract read
In one paragraph

Article in BMC medical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yuan Yuan *Department of Radiology, Changhai Hospital of Shanghai, No.168, Shanghai, China.
Shengnan Ren *Department of Nuclear Medicine, Shanghai Fourth People's Hospital, Shanghai, China.
Tiegong WangDepartment of Radiology, Changhai Hospital of Shanghai, No.168, Shanghai, China.
Fu ShenDepartment of Radiology, Changhai Hospital of Shanghai, No.168, Shanghai, China. ssff_53@163.com.ORCID 0000-0001-8596-9563
Qiang HaoDepartment of Radiology, Changhai Hospital of Shanghai, No.168, Shanghai, China.
Jianping LuDepartment of Radiology, Changhai Hospital of Shanghai, No.168, Shanghai, China.
Second Military Medical University · CNThe Fourth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo explore the diagnostic value of three different measurement approaches in differentiating T1a-T1b from T2 gastric cancer (GC) lesions.

methodsA total of 95 consecutive patients with T1a-T2 stage of GC who performed preoperative MRI were retrospectively enrolled between January 2017 and November 2020. The parameters MRI T stage (subjective evaluation), thickness, maximum area and volume of the lesions were evaluated by two radiologists. Specific indicators including AUC, optimal cutoff, sensitivity, specificity, accuracy, positive likelihood ratio (PLR), negative likelihood ratio (NLR), positive predictive value (PPV) and negative predictive value (NPV) of MRI T stage, thickness, maximum area and volume for differentiating T1a-T1b from T2 stage lesions were calculated. The ROC curves were compared by the Delong test. Decision curve analysis (DCA) was used to evaluate the clinical benefit.

resultsThe ROC curves for thickness (AUC = 0.926), maximum area (AUC = 0.902) and volume (AUC = 0.897) were all significantly better than those of the MRI T stage (AUC = 0.807) in differentiating T1a-T1b from T2 lesions, with p values of 0.004, 0.034 and 0.041, respectively. The values corresponding to the thickness (including AUC, sensitivity, specificity, accuracy, PPV, NPV, PLR and NLR) were all higher than those corresponding to the MRI T stage, maximum area and volume. The DCA curves indicated that the parameter thickness could provide the highest clinical benefit if the threshold probability was above 35%.

conclusionsThickness may provide an efficient approach to rapidly distinguish T1a-T1b from T2 stage GC lesions.

Indexed as

AgedDiagnosis, DifferentialFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeoplasm StagingObserver VariationRetrospective StudiesROC CurveStomach NeoplasmsGastric cancerMagnetic resonance imagingThicknessT stagingVolume

Identifiers

PMID34583642
PMCPMC8480061
OpenAlexW3169674627

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.