Evidence map›Paper›PMID 34583454›Full record

ArticleCancer research and treatment2022

Predictive Value of Interstitial Lung Abnormalities for Postoperative Pulmonary Complications in Elderly Patients with Early-stage Lung Cancer.

Won Gi Jeong, Yun-Hyeon Kim, Jong Eun Lee, In-Jae Oh, Sang Yun Song, Kum Ju Chae, Hye Mi Park

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer research and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Won Gi JeongLung and Esophageal Cancer Clinic, Chonnam National University, Hwasun Hospital, Hwasun, Korea.
Yun-Hyeon KimDepartment of Radiology, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, Korea.
Jong Eun LeeDepartment of Radiology, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, Korea.
In-Jae OhLung and Esophageal Cancer Clinic, Chonnam National University, Hwasun Hospital, Hwasun, Korea.
Sang Yun SongLung and Esophageal Cancer Clinic, Chonnam National University, Hwasun Hospital, Hwasun, Korea.
Kum Ju ChaeDepartment of Radiology, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea.
Hye Mi ParkLung and Esophageal Cancer Clinic, Chonnam National University, Hwasun Hospital, Hwasun, Korea.
Cancer Clinic · USChonnam National University Hospital · KRJeonbuk National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIdentifying pretreatment interstitial lung abnormalities (ILAs) is important because of their predictive value for complications after lung cancer treatment. This study aimed to assess the predictive value of ILAs for postoperative pulmonary complications (PPCs) in elderly patients undergoing curative resection for early-stage non-small cell lung cancer (NSCLC). MATERIALS AND

methodsElderly patients (age ≥ 70 years) who underwent curative resection for pathologic stage I or II NSCLC with normal preoperative spirometry results (pre-bronchodilator forced expiratory volume in 1 s to forced vital capacity [FVC] ratio > 0.70 and FVC ≥ 80% of the predicted value) between January 2012 and December 2019 were retrospectively identified. Univariable and multivariable regression analyses were performed to assess risk factors for PPCs. The Kaplan-Meier method and log-rank test were used to analyze the relationship between ILAs and postoperative mortality. One-way analysis of variance was performed to assess the correlation between ILAs and hospital stay duration.

resultsA total of 262 patients (median age, 73 [interquartile range, 71-76] years; 132 male) were evaluated. A multivariable logistic regression model revealed that, among several relevant risk factors, fibrotic ILAs independently predicted both overall PPCs (adjusted odds ratio [OR], 4.84; 95% confidence interval [CI], 1.35-17.38; p=0.016) and major PPCs (adjusted OR, 8.72; 95% CI, 1.71-44.38; p=0.009). Fibrotic ILAs were significantly associated with higher postoperative mortality and longer hospital stay (F=5.21, p=0.006).

conclusionPretreatment fibrotic ILAs are associated with PPCs, higher postoperative mortality, and longer hospital stay.

Indexed as

Carcinoma, Non-Small-Cell LungLung Diseases, InterstitialLung NeoplasmsSmall Cell Lung CarcinomaAgedHumansLungMalePostoperative ComplicationsRetrospective StudiesRisk FactorsEarly-stage non-small cell lung cancerElderly patientsInterstitial lung abnormalityPostoperative pulmonary complicationPreoperative risk stratification

Identifiers

PMID34583454
PMCPMC9296932
OpenAlexW3203048015

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.