Evidence map›Paper›PMID 34583336›Full record

ArticleThe American journal of tropical medicine and hygiene2021

Knowledge, Perceptions, and Attitudes Regarding Antibiotic Use for Lower Respiratory Tract Infections: Insights from Patients in Sri Lanka.

David T van Melle, Guus Ten Asbroek, Robert Rolfe, Sky Vanderburg, Yohanna W Abeysinghe, Chathuh Halloluwa, Helen L Zhang, Truls Ostbye, Ruvini Kurukulasooriya, Tianchen Sheng and 8 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

David T van MelleAmsterdam University Medical Center, Department of Global Health, Amsterdam, The Netherlands.
Guus Ten AsbroekAmsterdam University Medical Center, Department of Global Health, Amsterdam, The Netherlands.
Robert RolfeDuke Global Health Institute, Durham, North Carolina.
Sky VanderburgDuke University School of Medicine, Department of Medicine, Durham, North Carolina.
Yohanna W AbeysingheFaculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Chathuh HalloluwaFaculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Helen L ZhangDuke University School of Medicine, Department of Medicine, Durham, North Carolina.
Truls OstbyeDuke Global Health Institute, Durham, North Carolina.
Ruvini KurukulasooriyaFaculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Tianchen ShengDuke Global Health Institute, Durham, North Carolina.
Sewwandi KanchanaFaculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Gaya WijayaratneFaculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Champica BodinayakeDuke Global Health Institute, Durham, North Carolina.
Ajith NagahawatteDuke Global Health Institute, Durham, North Carolina.
Melissa H WattDuke Global Health Institute, Durham, North Carolina.
Christopher W WoodsDuke Global Health Institute, Durham, North Carolina.
Vijitha de SilvaDuke Global Health Institute, Durham, North Carolina.
Gayani TillekeratneDuke Global Health Institute, Durham, North Carolina.

Funding

MUTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007185 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI David J Erle, LAURENCE HUANG · 1985 to 2026
$24.6M
Novel Diagnostics to Improve Antimicrobial Stewardship for Acute Respiratory Tract Infections in Resource-Limited SettingsK23AI125677 · NIAID · DUKE UNIVERSITY · PI TILLEKERATNE, GAYANI · 2017 to 2021
$905k
NHLBI NIH HHS T32 HL007185NIAID NIH HHS K23 AI125677
6 · The paper itself

Abstract

Antibiotic resistance is an emerging global public health threat. One of the main drivers of this threat is the inappropriate use of antibiotics. In Sri Lanka, antibiotic consumption is increasing, but little is known locally about how patients perceive antibiotics. We conducted a qualitative study to gain a better understanding of the knowledge, perceptions, and attitudes of patients regarding antibiotics and antibiotic resistance. Semi-structured interviews involving 18 patients with lower respiratory tract infection (LRTI) admitted to a large, public tertiary care hospital in southern Sri Lanka were conducted. Interviews were analyzed to identify themes regarding the patients' knowledge of LRTI etiology and treatment, perceptions and attitudes toward LRTI treatment, including antibiotics, and patient-physician communication. Most patients mentioned multiple care visits and the use of multiple pharmaceuticals prior to admission. Patients sought a quick resolution to their ailments and frequently visited several private physicians to obtain a satisfying answer. Self-medication was also common. Patients reused prescriptions for antibiotics, kept antibiotics for later use after prematurely stopping their course of treatment, and bought over-the-counter antibiotics. Patients' knowledge of disease etiology and antibiotics was poor. Only a few patients were aware of antibiotic resistance. Despite the desire to receive more information regarding disease and treatment, patient-provider communication was limited and mainly confined to prescription instructions. This qualitative study performed in Sri Lanka suggests that inappropriate use of antibiotics is a multifactorial problem. To improve antibiotic use, a multifactorial approach that includes educating the public, increasing awareness among physicians, and implementing systems-level changes to restrict access to antibiotics is urgently needed.

Indexed as

Health Knowledge, Attitudes, PracticeAdultAdverse Drug Reaction Reporting SystemsAnti-Bacterial AgentsFemaleHumansMaleRespiratory Tract InfectionsSri LankaSurveys and QuestionnairesYoung AdultAnti-Bacterial Agents

Identifiers

PMID34583336
PMCPMC8641348

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.