ReviewCurrent opinion in neurobiology2021
Non-REM and REM/paradoxical sleep dynamics across phylogeny.
Review in Current opinion in neurobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 36 citations in OpenAlex.
- The Sentinel Sleep Theory: Unweaving the biological function of REM sleep.Sleep medicine: X · 2026Article
- Invertebrate brains as diversified models for understanding sleep mechanisms and function.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Review
- Nighttime sleep promotes mechanosensory habituation inbioRxiv : the preprint server for biology · 2026Article
- Zebrafish sleep displays distinct sub-states.iScience · 2026Article
- Characteristics of the sleep structure in the cleaner wrasse Labroides dimidiatus.Zoological letters · 2026Article
- A novel theory of rapid eye movement sleep as an integral component of the seasonal timekeeping apparatus.Frontiers in neuroscience · 2026Article
- Non-invasive wireless electroencephalographic recording of the sleep-wake cycle in freely moving reptiles, birds, and mammals: a novel methodology compatible with animal welfare.Frontiers in veterinary science · 2026Article
- Sleep Patterns and Human Brain Health.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2025Review
- Zebrafish sleep displays distinct sub-states.bioRxiv : the preprint server for biology · 2025Article
- Interictal network dysfunction and cognitive impairment in epilepsy.Nature reviews. Neuroscience · 2025Review
- Article
- The interplay between sleep and ecophysiology, behaviour and responses to environmental change in fish.The Journal of experimental biology · 2024Review
- Phylogenetic conservation of the interdependent homeostatic relationship of sleep regulation and redox metabolism.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024Review
- Generalized sleep decoding with basal ganglia signals in multiple movement disorders.NPJ digital medicine · 2024Article
- Multivariate classification of multichannel long-term electrophysiology data identifies different sleep stages in fruit flies.Science advances · 2024Article
- Evo-devo applied to sleep research: an approach whose time has come.Sleep advances : a journal of the Sleep Research Society · 2024Review
- The Wave Model of Sleep Dynamics and an Invariant Relationship between NonREM and REM Sleep.Clocks & sleep · 2023Article
- Experimentally induced active and quiet sleep engage non-overlapping transcriptional programs ineLife · 2023Article
- Experimentally induced active and quiet sleep engage non-overlapping transcriptional programs inbioRxiv : the preprint server for biology · 2023Article
- Temporal Feature Extraction and Machine Learning for Classification of Sleep Stages Using Telemetry Polysomnography.Brain sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
All animals carefully studied sleep, suggesting that sleep as a behavioral state exists in all animal life. Such evolutionary maintenance of an otherwise vulnerable period of environmental detachment suggests that sleep must be integral in fundamental biological needs. Despite over a century of research, the knowledge of what sleep does at the tissue, cellular or molecular levels remain cursory. Currently, sleep is defined based on behavioral criteria and physiological measures rather than at the cellular or molecular level. Physiologically, sleep has been described as two main states, non-rapid eye moment (NREM) and REM/paradoxical sleep (PS), which are defined in the neocortex by synchronous oscillations and paradoxical wake-like activity, respectively. For decades, these two sleep states were believed to be defining characteristics of only mammalian and avian sleep. Recent work has revealed slow oscillation, silencing, and paradoxical/REM-like activities in reptiles, fish, flies, worms, and cephalopods suggesting that these sleep dynamics and associated physiological states may have emerged early in animal evolution. Here, we discuss these recent developments supporting the conservation of neural dynamics (silencing, oscillation, paradoxical activity) of sleep states across phylogeny.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.