Observational studyNutrition (Burbank, Los Angeles County, Calif.)
Qualitative and quantitative muscle ultrasound changes in patients with COVID-19-related ARDS.
Observational study in Nutrition (Burbank, Los Angeles County, Calif.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06289244 (Correlation Between Muscle Strength and Thickness in Critically Ill Patients), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Correlation Between Muscle Strength and Thickness in Critically Ill Patients: an Observational Prospective Study
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and clinical implications of abnormal body composition phenotypes in patients with COVID-19: a systematic review.The American journal of clinical nutrition · 2023Pooled it
- Ultrasound assessment of muscle atrophy and its association with functional outcomes in critically ill patients: a systematic review and meta-analysis.Critical care (London, England) · 2026Review
- Assessment of muscle wasting in intensive care unit patients with and without COVID-19 using ultrasound imaging and bioimpedance analysis.BMC anesthesiology · 2026Article
- Ultrasound innovations in diaphragm assessment: an integrative review of expanding clinical applications.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- The effect of mechanical ventilation on respiratory muscle echogenicity in critically ill children: an observational cohort study.BMC pediatrics · 2025Observational
- Ultrasound-Derived Skinfolds in Anthropometric Predictive Equations Overestimate Fat Mass: A Validation Study Using a Four-Component Model.Nutrients · 2025Article
- Diaphragm thickness and ICU admission risk in elderly COVID-19 patients: a CT-based analysis.BMC pulmonary medicine · 2025Article
- Methodologies and clinical applications of lower limb muscle ultrasound in critically ill patients: a systematic review and meta-analysis.Annals of intensive care · 2024Review
- Diaphragm Muscle Atrophy Contributes to Low Physical Capacity in COVID-19 Survivors.Life (Basel, Switzerland) · 2024Article
- Incorporating ultrasonography to the nutritional assessment process in intensive care settings to improve the prescription of enteral and parenteral nutrition: Benefits, practicality, and challenges.Saudi medical journal · 2024Review
- Diaphragm Ultrasound in Different Clinical Scenarios: A Review with a Focus on Older Patients.Geriatrics (Basel, Switzerland) · 2024Review
- Nutritional and Morphofunctional Assessment of Post-ICU Patients with COVID-19 at Hospital Discharge: NutriEcoMuscle Study.Nutrients · 2024Observational
- Muscle Dysfunction and Functional Status in COVID-19 Patients during Illness and after Hospital Discharge.Biomedicines · 2024Article
- Bioimpedance-assessed muscle wasting and its relation to nutritional intake during the first week of ICU: a pre-planned secondary analysis of Nutriti Study.Annals of intensive care · 2024Article
- A High Respiratory Drive Is Associated with Weaning Failure in Patients with COVID-19-Associated Acute Respiratory Distress Syndrome: The Role of the Electrical Activity of the Diaphragm.Journal of clinical medicine · 2024Article
- Prolonged intensive care: muscular functional, and nutritional insights from the COVID-19 pandemic.Acute and critical care · 2024Article
- Ultrasonographic Features of Muscular Weakness and Muscle Wasting in Critically Ill Patients.Journal of clinical medicine · 2023Review
- Muscle ultrasound and its application to point-of-care ultrasonography: a narrative review.Annals of medicine · 2023Review
- Nutritional support and prevention of post-intensive care syndrome: the Italian SIAARTI survey.Journal of anesthesia, analgesia and critical care · 2023Article
- Extended prone positioning for intubated ARDS: a review.Critical care (London, England) · 2023Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesSevere forms of the novel coronavirus-19 (COVID-19) are associated with systemic inflammation and hypercatabolism. The aims of this study were to compare the time course of the size and quality of both rectus femoris and diaphragm muscles between critically ill, COVID-19 survivors and non-survivors and to explore the correlation between the change in muscles size and quality with the amount of nutritional support delivered and the cumulative fluid balance.
methodsThis was a prospective observational study in the general intensive care unit (ICU) of a tertiary care hospital for COVID-19. The right rectus femoris cross-sectional area and the right diaphragm thickness, as well as their echo densities were assessed within 24 h from ICU admission and on day 7. We recorded anthropometric and biochemical data, respiratory mechanics and gas exchange, daily fluid balance, and the number of calories and proteins administered.
resultsTwenty-eight patients were analyzed (65 ± 10 y of age; 80% men, body mass index 30 ± 7.8 kg/m
conclusionsEarly changes in muscle size and quality seem related to the outcome of critically ill COVID-19 patients, and to be influenced by nutritional and fluid management strategies.
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