Evidence map›Paper›PMID 34582813›Full record

ArticleCurrent biology : CB2021

Cell biology: How does the nucleus get its membrane?

Orna Cohen-Fix

Open access · greenAbstract readComment
In one paragraph

Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. A multiomics atlas of theScience advances · 2026
    Article
  3. A STEDable BFMembranes · 2025
    Article
  4. Organelle Communication with the Nucleus.Results and problems in cell differentiation · 2024
    Review
  5. PEDF Deletion Induces Senescence and Defects in Phagocytosis in the RPE.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Orna Cohen-FixThe Laboratory of Biochemistry and Genetics, NIDDK, NIH, Bethesda, MD 20892, USA. Electronic address: ornac@niddk.nih.gov.
National Institutes of Health · US

Funding

Nuclear architecture in C. elegansZIADK069012 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI COHEN-FIX, ORNA · 2009 to 2025
$9.9M
Biotechnology and Biological Sciences Research Council BB/R009732/1Intramural NIH HHS ZIA DK069012
6 · The paper itself

Abstract

Nuclear shape and size depend on nuclear membrane availability through an unknown process. A new study of asymmetric cell division reveals that nuclear membrane is derived from the endoplasmic reticulum and that limiting nuclear membrane expansion can affect cell fate.

Indexed as

Cell NucleusNuclear EnvelopeAsymmetric Cell DivisionEndoplasmic Reticulum

Identifiers

PMID34582813
PMCPMC10281029
OpenAlexW3203627695

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.