Evidence map›Paper›PMID 34582561›Full record

SynthesisScandinavian journal of work, environment & health2022

Job strain and effort-reward imbalance as risk factors for type 2 diabetes mellitus: A systematic review and meta-analysis of prospective studies.

Ana Paula B Pena-Gralle, Denis Talbot, Caroline S Duchaine, Mathilde Lavigne-Robichaud, Xavier Trudel, Karine Aubé, Matthias Gralle, Mahée Gilbert-Ouimet, Alain Milot, Chantal Brisson

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Scandinavian journal of work, environment & health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. Review
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  7. Article
  8. Hard road to climb: blunted academic and professional trajectories and effort-reward imbalance for people with narcolepsy type 1.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
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  18. Cognitive Job Demands and Sports Participation among Young Workers: What Moderates the Relationship?International journal of environmental research and public health · 2024
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Ana Paula B Pena-GralleCHU de Québec Research Center, Population Health and Optimal Health Practices Unit, Saint-Sacrément Hospital, 1050, Chemin Ste-Foy, Québec, QC, Canada G1S 4L8. ana-paula.bruno-pena-gralle.1@ulaval.ca.
Denis Talbot
Caroline S Duchaine
Mathilde Lavigne-Robichaud
Xavier Trudel
Karine Aubé
Matthias Gralle
Mahée Gilbert-Ouimet
Alain Milot
Chantal Brisson
The Quebec Population Health Research Network · CAUniversidade Federal do Rio de Janeiro · BRHôpital du Saint-Sacrement · CA

Funding

CIHR MOP-119280
6 · The paper itself

Abstract

objectivesThis systematic review and meta-analysis aimed to synthesize the available data on prospective associations between work-related stressors and the risk of type 2 diabetes mellitus (T2DM) among adult workers, according to the demand-control-support (DCS) and the effort-reward imbalance (ERI) models.

methodWe searched for prospective studies in PubMed, EMBASE, Web of Science, Scopus, CINHAL and PsychInfo. After screening and extraction, quality of evidence was assessed using the ROBINS-I tool adapted for observational studies. The effect estimates extracted for each cohort were synthesized using random effect models.

resultsWe included 18 studies (reporting data on 25 cohorts) in meta-analyses for job strain, job demands, job control, social support at work and ERI. Workers exposed to job strain had a higher risk of developing T2DM when compared to unexposed workers [pooled rate ratio (RR) 1.16, 95% confidence interval (CI) 1.07-1.26]. This association was robust in several supplementary analyses. For exposed women relative to unexposed women, the RR was 1.35 (95% CI 1.12-1.64). The RR of workers exposed to ERI was 1.24 (95% CI 1.08-1.42) compared to unexposed workers.

conclusionsThis is the first meta-analysis to find an effect of ERI on the onset of T2DM incidence. It also confirms that job strain increases the incidence of T2DM, especially among women.

Indexed as

Diabetes Mellitus, Type 2AdultFemaleHumansProspective StudiesRewardRisk FactorsStress, Psychological

Identifiers

PMID34582561
PMCPMC8729162
OpenAlexW3204070110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.