Evidence map›Paper›PMID 34582449›Full record

Trial reportPLoS medicine2021

Cost-effectiveness and economic returns of group-based parenting interventions to promote early childhood development: Results from a randomized controlled trial in rural Kenya.

Italo Lopez Garcia, Uzaib Y Saya, Jill E Luoto

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PLoS medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03548558 (Testing Means to Scale Early Childhood Development Interventions in Rural Kenya), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03548558 nacompletednot on this map

Testing Means to Scale Early Childhood Development Interventions in Rural Kenya

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2018 to 2021Enrolled1,152ConditionsEarly Child DevelopmentArmsGroup sessions, Group+Home sessions, Booster sessions, Fathers invited
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Italo Lopez GarciaRAND Corporation, Santa Monica, California, United States of America.ORCID 0000-0003-3931-2290
Uzaib Y SayaRAND Corporation, Santa Monica, California, United States of America.
Jill E LuotoRAND Corporation, Santa Monica, California, United States of America.ORCID 0000-0001-7231-9633

Funding

Testing Means to Scale Early Childhood Development Interventions in Rural KenyaR01HD090045 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LUOTO, JILL · 2017 to 2021
$3.3M
Achieving Sustained Early Child Development Impacts at Scale: a Kenyan RCTR01HD107116 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Italo Lopez Garcia · 2022 to 2026
$3.2M
Pathways and Mediators of Change in Early Childhood DevelopmentR21HD099488 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LOPEZ GARCIA, ITALO · 2020 to 2021
$420k
NICHD NIH HHS R01 HD090045NICHD NIH HHS R01 HD107116NICHD NIH HHS R21 HD099488
6 · The paper itself

Abstract

backgroundEarly childhood development (ECD) programs can help address disadvantages for the 43% of children under 5 in low- and middle-income countries (LMICs) experiencing compromised development. However, very few studies from LMIC settings include information on their program's cost-effectiveness or potential returns to investment. We estimated the cost-effectiveness, benefit-cost ratios (BCRs), and returns on investment (ROIs) for 2 effective group-based delivery models of an ECD parenting intervention that utilized Kenya's network of local community health volunteers (CHVs). METHODS AND

findingsBetween October 1 and November 12, 2018, 1,152 mothers with children aged 6 to 24 months were surveyed from 60 villages in rural western Kenya. After baseline, villages were randomly assigned to one of 3 intervention arms: a group-only delivery model with 16 fortnightly sessions, a mixed-delivery model combining 12 group sessions with 4 home visits, and a control group. At endline (August 5 to October 31, 2019), 1,070 children were retained and assessed for primary outcomes including cognitive and receptive language development (with the Bayley Scales of Infant Development, Third Edition) and socioemotional development (with the Wolke scale). Children in the 2 intervention arms showed better developmental outcomes than children in the control arm, although the group-only delivery model generally had larger effects on children. Total program costs included provider's implementation costs collected during the intervention period using financial reports from the local nongovernmental organization (NGO) implementer, as well as societal costs such as opportunity costs to mothers and delivery agents. We combined program impacts with these total costs to estimate incremental cost-effectiveness ratios (ICERs), as well as BCRs and the program's ROI for the government based on predictions of future lifetime wages and societal costs. Total costs per child were US$140 in the group-only arm and US$145 in the mixed-delivery arm. Because of higher intention-to-treat (ITT) impacts at marginally lower costs, the group-only model was the most cost-effective across all child outcomes. Focusing on child cognition in this arm, we estimated an ICER of a 0.37 standard deviation (SD) improvement in cognition per US$100 invested, a BCR of 15.5, and an ROI of 127%. A limitation of our study is that our estimated BCR and ROI necessarily make assumptions about the discount rate, income tax rates, and predictions of intervention impacts on future wages and schooling. We examine the sensitivity of our results to these assumptions.

conclusionsTo the best of our knowledge, this study is the first economic evaluation of an effective ECD parenting intervention targeted to young children in sub-Saharan Africa (SSA) and the first to adopt a societal perspective in calculating cost-effectiveness that accounts for opportunity costs to delivery agents and program participants. Our cost-effectiveness and benefit-cost estimates are higher than most of the limited number of prior studies from LMIC settings providing information about costs. Our results represent a strong case for scaling similar interventions in impoverished rural settings, and, under reasonable assumptions about the future, demonstrate that the private and social returns of such investments are likely to largely outweigh their costs.

trial registrationThis trial is registered at ClinicalTrials.gov, NCT03548558, June 7, 2018. American Economic Association RCT Registry trial AEARCTR-0002913.

Indexed as

Child DevelopmentParentingAdolescentAdultChild, PreschoolCost-Benefit AnalysisDelivery of Health CareDevelopmental DisabilitiesFemaleHealth EducationHumansInfantLanguage DevelopmentMaleMothersRural Population

Identifiers

PMID34582449
PMCPMC8478245

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.