ArticlePLoS biology2021
Stimulation of the left dorsolateral prefrontal cortex with slow rTMS enhances verbal memory formation.
Article in PLoS biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Use of transcranial magnetic stimulation (TMS) for studying cognitive control in depressed patients: A systematic review.Cognitive, affective & behavioral neuroscience · 2024Pooled it
- Enhanced episodic memory and LTP-like plasticity in subjective cognitive decline following 10-Hz repetitive transcranial magnetic stimulation.Journal of neuroengineering and rehabilitation · 2025Trial
- Medial Prefrontal Cortex Stimulation Reduces Retrieval-Induced Forgetting via Fronto-parietal Beta Desynchronization.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Trial
- Early efficacy of rTMS intervention at week 2 predicts subsequent responses at week 24 in schizophrenia in a randomized controlled trial.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024Trial
- Resting-state neural oscillations predict individual differences in verbal learning and encoding strategy use.iScience · 2026Article
- Top-down influence of the inferior frontal gyrus on motor cortex excitability during pain empathy.Communications biology · 2026Article
- The Impact of Transcranial Magnetic Stimulation on Symptoms of Attention Deficit Hyperactivity Disorder and Sleep Parameters: Preliminary Study.Bioengineering (Basel, Switzerland) · 2026Article
- Article
- From Correlation to Causation: Understanding Episodic Memory Networks.Neuroscience bulletin · 2025Review
- Study on the clinical efficacy of repetitive transcranial magnetic stimulation in adolescent patients with depression and its influence on neurotransmitters based on functional near-infrared spectroscopy.Frontiers in psychiatry · 2025Article
- Lateral prefrontal theta oscillations causally drive a computational mechanism underlying conflict expectation and adaptation.Nature communications · 2024Article
- The maintenance of complex visual scenes in working memory may require activation of working memory manipulation circuits in the dlPFC: a preliminary report.Mental health science · 2024Article
- Transcranial Magnetic Stimulation in Disorders of Consciousness: An Update and Perspectives.Aging and disease · 2023Review
- No effects of 1 Hz offline TMS on performance in the stop-signal game.Scientific reports · 2023Article
- The role of dlPFC laterality in the expression and regulation of anxiety.Neuropharmacology · 2023Review
- Disturbing the activity of the primary motor cortex by means of transcranial magnetic stimulation affects long term memory of sentences referred to manipulable objects.Frontiers in psychology · 2023Article
- Edible Mushrooms as a Potential Component of Dietary Interventions for Major Depressive Disorder.Foods (Basel, Switzerland) · 2022Review
- Correction: Stimulation of the left dorsolateral prefrontal cortex with slow rTMS enhances verbal memory formation.PLoS biology · 2021Article
- Can brain stimulation boost memory performance?PLoS biology · 2021Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Encoding of episodic memories relies on stimulus-specific information processing and involves the left prefrontal cortex. We here present an incidental finding from a simultaneous EEG-TMS experiment as well as a replication of this unexpected effect. Our results reveal that stimulating the left dorsolateral prefrontal cortex (DLPFC) with slow repetitive transcranial magnetic stimulation (rTMS) leads to enhanced word memory performance. A total of 40 healthy human participants engaged in a list learning paradigm. Half of the participants (N = 20) received 1 Hz rTMS to the left DLPFC, while the other half (N = 20) received 1 Hz rTMS to the vertex and served as a control group. Participants receiving left DLPFC stimulation demonstrated enhanced memory performance compared to the control group. This effect was replicated in a within-subjects experiment where 24 participants received 1 Hz rTMS to the left DLPFC and vertex. In this second experiment, DLPFC stimulation also induced better memory performance compared to vertex stimulation. In addition to these behavioural effects, we found that 1 Hz rTMS to DLPFC induced stronger beta power modulation in posterior areas, a state that is known to be beneficial for memory encoding. Further analysis indicated that beta modulations did not have an oscillatory origin. Instead, the observed beta modulations were a result of a spectral tilt, suggesting inhibition of these parietal regions. These results show that applying 1 Hz rTMS to DLPFC, an area involved in episodic memory formation, improves memory performance via modulating neural activity in parietal regions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.