Evidence map›Paper›PMID 34582045›Full record

ReviewAnnals of human genetics2022

Tools for standardized data collection: Speech, Language, and Hearing measurement protocols in the PhenX Toolkit.

Cynthia C Morton, Mary L Marazita, Beate Peter, Mabel L Rice, Shelly Jo Kraft, Julie Barkmeier-Kraemer, Carey Balaban, Michael Phillips, Jennifer Schoden, Deborah Maiese and 2 more

Open access · hybridAbstract readReview
In one paragraph

Review in Annals of human genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Cynthia C MortonBrigham and Women's Hospital, Harvard Medical School, Broad Institute of MIT and Harvard, University of Manchester, Manchester, UK.
Mary L MarazitaUniversity of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Beate PeterArizona State University, Phoenix, Arizona, USA.ORCID 0000-0002-9083-8522
Mabel L RiceUniversity of Kansas, Lawrence, Kansas, USA.
Shelly Jo KraftWayne State University, Detroit, Michigan, USA.
Julie Barkmeier-KraemerUniversity of Utah, Salt Lake City, Utah, USA.
Carey BalabanUniversity of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Michael PhillipsRTI International, Research Triangle Park, North Carolina, USA.
Jennifer SchodenRTI International, Research Triangle Park, North Carolina, USA.
Deborah MaieseRTI International, Research Triangle Park, North Carolina, USA.
Tabitha HendershotRTI International, Research Triangle Park, North Carolina, USA.
Carol M HamiltonRTI International, Research Triangle Park, North Carolina, USA.
RTI International · USUniversity of Pittsburgh · USArizona State University · USBroad Institute · USUniversity of Kansas · USUniversity of Utah · USWayne State University · US

Funding

Genomic Resource Grant for the PhenX Toolkit - expansion and sustainabilityPhenX Supplement for COVID-19 ResearchU41HG007050 · NHGRI · RESEARCH TRIANGLE INSTITUTE · PI HAMILTON, CAROL MARIE · 2013 to 2022
$21.2M
TRAINING GRANT IN GENETICST32GM007748 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Anne O'Donnell-Luria, Louise Wilkins-Haug · 1985 to 2026
$12.0M
MORPHOSYNTACTIC ABILITIES OF SLI PROBANDS AND FAMILIESR01DC001803 · NIDCD · UNIVERSITY OF KANSAS LAWRENCE · PI RICE, MABEL L · 1993 to 2022
$10.9M
Twins and Singletons with Specific Language ImpairmentR01DC005226 · NIDCD · UNIVERSITY OF KANSAS LAWRENCE · PI RICE, MABEL L · 2002 to 2016
$8.3M
SEQuencing a Baby for an Optimal Outcome (SEQaBOO)R01DC015052 · NIDCD · BRIGHAM AND WOMEN'S HOSPITAL · PI MORTON, CYNTHIA CASSON · 2016 to 2020
$3.8M
TRAINING RESEARCHERS IN LANGUAGE IMPAIRMENTST32DC000052 · NIDCD · UNIVERSITY OF KANSAS LAWRENCE · PI RICE, MABEL L · 1995 to 2022
$2.7M
Development of a new approach to screening for language impairmentsR42DC013749 · NIDCD · PANTHER TECHNOLOGY · PI ELLENSON, RICHARD, RICE, MABEL L · 2013 to 2019
$998k
An Innovative Screener for Reading and SLI targeting Kindergarten through 3rd Grade StudentsR43DC018766 · NIDCD · AMIRA LEARNING, INC. · PI ANGEL, MARK, RICE, MABEL L · 2021 to 2021
$257k
NHGRI NIH HHS U41 HG007050NIDCD NIH HHS R01 DC001803NIDCD NIH HHS R01 DC005226NIDCD NIH HHS R01 DC015052NIDCD NIH HHS R42 DC013749NIDCD NIH HHS R43 DC018766NIDCD NIH HHS T32 DC000052NIGMS NIH HHS T32 GM007748
6 · The paper itself

Abstract

The PhenX Toolkit (https://www.phenxtoolkit.org/) is an online catalog of recommended measurement protocols to facilitate cross-study analyses for biomedical research. An expert review panel (ERP) reviewed and updated the PhenX Toolkit Speech and Hearing domain to improve the precision and consistency of speech, language, and hearing disorder phenotypes. A three-member ERP convened in August 2018 to review the measurement protocols in the PhenX Speech and Hearing domain. Aided by three additional experts in voice assessment, vertigo, and stuttering, the ERP updated the 28 protocols to reflect the latest science and technology. ERP recommendations include six new protocols, five updated protocols (from the same source), and one retired protocol. New additions include two voice-related, three hearing-related, and two speech-related protocols. Additions reflect new phone/tablet applications for hearing and language, and clinical evaluations of voice. "Language" was added to the domain name, which is now "Speech, Language, and Hearing," to represent language-related protocols. These protocols can facilitate the assessment of speech, language, and hearing in clinical and population research. Common data elements (i.e., use of the same variables across studies) used by geneticists, otolaryngologists, audiologists, speech-language pathologists, and in other disciplines can lead to cross-study data integration and increased statistical power when studies are combined.

Indexed as

Research DesignSpeechHearingHumansPhenotypecommon data elementshearinglanguagephenotypesPhenX Toolkitspeechstandardized measurement protocol

Identifiers

PMID34582045
PMCPMC8725989
OpenAlexW3201071433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.