Evidence map›Paper›PMID 34582023›Full record

ArticleAdvances in experimental medicine and biology2021

Decellularization of Skin Tissue.

Naveen Kumar, Vineet Kumar, Sanjay Purohit, Anil Kumar Gangwar, Sameer Shrivastava, Swapan Kumar Maiti, Sonal Saxena, Dayamon David Mathews, Pawan Diwan Singh Raghuvanshi, Ajit Kumar Singh and 1 more

Abstract read
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In one paragraph

Article in Advances in experimental medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
9.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Mesenchymal stem cells express epidermal markers in anFrontiers in cell and developmental biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Naveen KumarDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India. naveen.ivri1961@gmail.com.
Vineet KumarDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Sanjay PurohitDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Anil Kumar GangwarDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Sameer ShrivastavaDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Swapan Kumar MaitiDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Sonal SaxenaDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Dayamon David MathewsDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Pawan Diwan Singh RaghuvanshiDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Ajit Kumar SinghDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Karam Pal SinghDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Indian Veterinary Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomaterials science encompasses elements of medicine, biology, chemistry, materials, and tissue engineering. They are engineered to interact with biological systems to treat, augment, repair, or replace lost tissue function. The choice of biomaterial depends on the procedure being performed, the severity of the patient's condition, and the surgeon's preference. Prostheses made from natural-derived biomaterials are often derived from decellularized extracellular matrix (ECM) of animal (xenograft) or human (allograft) origin. Advantages of using ECM include their resemblance in morphology and three-dimensional structures with that of tissue to be replaced. Due to this, scientists all over are now focusing on naturally derived biomaterials which have been shown to possess several advantages compared to synthetic ones, owing to their biocompatibility, biodegradability, and remodeling properties. Advantages of a naturally derived biomaterial enhance their application for replacement or restoration of damaged organs/tissues. They adequately support cell adhesion, migration, proliferation, and differentiation. Naturally derived biomaterials can induce extracellular matrix formation and tissue repair when implanted into a defect by enhancing attachment and migration of cells from surrounding environment. In the current chapter, we will focus on the natural and synthetic dermal matrix development and all of the progress in this field.

Indexed as

Tissue EngineeringTissue ScaffoldsAnimalsBiocompatible MaterialsCell AdhesionExtracellular MatrixHumansBiocompatible MaterialsDecellularizationDermal MatrixSkinTissue engineering

Identifiers

PMID34582023
OpenAlexW3204936160

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.