Evidence map›Paper›PMID 34581954›Full record

ReviewMolecular imaging and biology2022

In Vivo MRI Tracking of Tumor Vaccination and Antigen Presentation by Dendritic Cells.

Jeff W M Bulte, Ali Shakeri-Zadeh

Open access · bronzeAbstract readReview
In one paragraph

Review in Molecular imaging and biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Preclinical Applications of Magnetic Resonance Imaging in Oncology.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  3. Recent advances in non-invasiveBiomaterials science · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Advanced functional materials · 2022
    Article
  9. Article
  10. Review
  11. MRI techniques for immunotherapy monitoring.Journal for immunotherapy of cancer · 2022
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jeff W M BulteRussell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins University School of Medicine, MRB 659, 733 N. Broadway, MD, 21205, Baltimore, USA. jwmbulte@mri.jhu.edu.
Ali Shakeri-ZadehRussell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins University School of Medicine, MRB 659, 733 N. Broadway, MD, 21205, Baltimore, USA.
Johns Hopkins University · US

Funding

Training/Dissemination-Resource for Molecular Imaging Agents in Precision MedicineP41EB024495 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MARTIN G POMPER · 2017 to 2026
$11.8M
Precision magnetic hyperthermia by integrating magnetic particle imagingR01CA257557 · NCI · JOHNS HOPKINS UNIVERSITY · PI BULTE, JEFF W., IVKOV, ROBERT · 2021 to 2025
$3.2M
Intracellular Self-Assembly of Theranostic Nanoparticles for Enhanced Imaging and Tumor TherapyR01EB030376 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI BULTE, JEFF W. · 2020 to 2024
$2.1M
Dual-mode MRI for in vivo sensing of microcapsule stability and biocompatibilityR01DK106972 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI BULTE, JEFF W. · 2015 to 2018
$1.7M
Label-Free Imaging of Composite Hyaluronic Acid Hydrogels in Regenerative MedicineR01EB023647 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI BULTE, JEFF W. · 2017 to 2020
$1.5M
Magnetic Particle Imaging ScannerS10OD026740 · OD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI BULTE, JEFF W. · 2019 to 2019
$600k
Non-Invasive Tracking of Genome-Corrected iPS cells in ALSUH2EB028904 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI BULTE, JEFF W. · 2019 to 2020
$482k
NCI NIH HHS R01 CA257557NIBIB NIH HHS P41 EB024495NIBIB NIH HHS R01 EB023647NIBIB NIH HHS R01 EB030376NIBIB NIH HHS UH2 EB028904NIDDK NIH HHS R01 DK106972NIH HHS S10 OD026740
6 · The paper itself

Abstract

Cancer vaccination using tumor antigen-primed dendritic cells (DCs) was introduced in the clinic some 25 years ago, but the overall outcome has not lived up to initial expectations. In addition to the complexity of the immune response, there are many factors that determine the efficacy of DC therapy. These include accurate administration of DCs in the target tissue site without unwanted cell dispersion/backflow, sufficient numbers of tumor antigen-primed DCs homing to lymph nodes (LNs), and proper timing of immunoadjuvant administration. To address these uncertainties, proton (

Indexed as

Antigen PresentationDendritic CellsContrast MediaMagnetic Resonance ImagingVaccinationContrast MediaAntigen presentationCancer vaccinationCell trackingDendritic cellFluorine emulsionsMagnetic resonance imagingSuperparamagnetic iron oxide nanoparticles

Identifiers

PMID34581954
PMCPMC8477715
OpenAlexW3204545148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.