Evidence map›Paper›PMID 34581932›Full record

ArticleJournal of molecular histology2021

The combination of hair follicle-specific marker LHX2 and co-expressed marker can distinguish between sweat gland placodes and hair placodes in rat.

Manxiu Cao, Junhong Zhao, Lijie Du, Zixiu Chen, Lei Zhang, Xiang Liu, Jiaqi Cheng, Yongjing Yan, Cuiping Zhang, Haihong Li

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular histology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Foxa1 mediates eccrine sweat gland development through transcriptional regulation of Na-K-ATPase expression.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Manxiu Cao *Department of Wound Repair and Dermatologic Surgery, Jinzhou Medical University Graduate Training Base, Taihe Hospital, Hubei University of Medicine, 32 South Renmin Road, Shiyan, 442000, Hubei Province, China.
Junhong Zhao *Department of Wound Repair and Dermatologic Surgery, Jinzhou Medical University Graduate Training Base, Taihe Hospital, Hubei University of Medicine, 32 South Renmin Road, Shiyan, 442000, Hubei Province, China.
Lijie DuDepartment of Wound Repair and Dermatologic Surgery, Jinzhou Medical University Graduate Training Base, Taihe Hospital, Hubei University of Medicine, 32 South Renmin Road, Shiyan, 442000, Hubei Province, China.
Zixiu ChenDepartment of Wound Repair and Dermatologic Surgery, Jinzhou Medical University Graduate Training Base, Taihe Hospital, Hubei University of Medicine, 32 South Renmin Road, Shiyan, 442000, Hubei Province, China.
Lei ZhangMental Health Center, Taihe Hospital, Hubei University of Medicine, 32 South Renmin Road, Shiyan, 442000, Hubei Province, China.
Xiang LiuDepartment of Wound Repair and Dermatologic Surgery, Taihe Hospital, Hubei University of Medicine, 32 South Renmin Road, Shiyan, 442000, Hubei Province, China.
Jiaqi ChengDepartment of Wound Repair and Dermatologic Surgery, Taihe Hospital, Hubei University of Medicine, 32 South Renmin Road, Shiyan, 442000, Hubei Province, China.
Yongjing YanDepartment of Wound Repair and Dermatologic Surgery, Jinzhou Medical University Graduate Training Base, Taihe Hospital, Hubei University of Medicine, 32 South Renmin Road, Shiyan, 442000, Hubei Province, China.
Cuiping ZhangResearch Center for Tissue Repair and Regeneration affiliated to the Medical Innovation Research Department and Fourth Medical Center of PLA General Hospital, Beijing, 100048, China. zcp666666@sohu.com.
Haihong LiDepartment of Wound Repair and Dermatologic Surgery, Jinzhou Medical University Graduate Training Base, Taihe Hospital, Hubei University of Medicine, 32 South Renmin Road, Shiyan, 442000, Hubei Province, China. lihaihong1051@126.com.
Taihe Hospital · CNHubei University of Medicine · CNJinzhou Medical University · CNChinese PLA General Hospital · CN

Funding

National Natural Science Foundation of China 81772102National Natural Science Foundation of China 82172231
6 · The paper itself

Abstract

Eccrine sweat gland (ESG) and hair follicle (HF) are different skin appendages but share many common development characteristics. Although the morphology of adult ESG and HF is obviously different, it is difficult to distinguish ESG placodes from HFs placodes morphologically. To study the fate determination of ESG and HF, specific antigen markers for ESG placodes and HF placodes must be found first to distinguish them. In the study, we detected the expression of commonly used keratins 4, 5, 7-10, 12, 14, 15, 17-20, 27 and 73, and the reported ESG and HF specific markers, P-cadherin, Lymphoid enhancer factor 1 (LEF1), LIM Homeobox gene 2 (LHX2), Na

Indexed as

BiomarkersGene ExpressionAnimalsFluorescent Antibody TechniqueHair FollicleImmunohistochemistryKeratinsLIM-Homeodomain ProteinsMultigene FamilyRatsSkinSweat GlandsTranscription FactorsBiomarkersKeratinsLhx2 protein, ratLIM-Homeodomain ProteinsTranscription FactorsAntigen markersEccrine sweat gland placodesHair placodesSkin appendagesSpecific markers

Identifiers

PMID34581932
OpenAlexW3204620680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.