Evidence map›Paper›PMID 34581919›Full record

ArticleFish physiology and biochemistry2021

Memory regulation in feeding habit transformation to dead prey fish of Chinese perch (Siniperca chuatsi).

Linjie Shi, Jiao Li, Xu-Fang Liang, Shan He, Yaqi Dou, Jian Peng, Wenjing Cai, Hui Liang

Abstract read
PubMed Publisher
In one paragraph

Article in Fish physiology and biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Linjie ShiCollege of Fisheries, Chinese Perch Research Center, Huazhong Agricultural University, Wuhan, 430070, China.
Jiao LiCollege of Fisheries, Chinese Perch Research Center, Huazhong Agricultural University, Wuhan, 430070, China.
Xu-Fang LiangCollege of Fisheries, Chinese Perch Research Center, Huazhong Agricultural University, Wuhan, 430070, China. xufang_liang@hotmail.com.
Shan HeCollege of Fisheries, Chinese Perch Research Center, Huazhong Agricultural University, Wuhan, 430070, China. heshan@mail.hzau.edu.cn.
Yaqi DouCollege of Fisheries, Chinese Perch Research Center, Huazhong Agricultural University, Wuhan, 430070, China.
Jian PengCollege of Fisheries, Chinese Perch Research Center, Huazhong Agricultural University, Wuhan, 430070, China.
Wenjing CaiCollege of Fisheries, Chinese Perch Research Center, Huazhong Agricultural University, Wuhan, 430070, China.
Hui LiangCollege of Fisheries, Chinese Perch Research Center, Huazhong Agricultural University, Wuhan, 430070, China.
Huazhong Agricultural University · CN

Funding

China Agriculture Research System CARS-46National Natural Science Foundation of China 31602131National Natural Science Foundation of China 31772822
6 · The paper itself

Abstract

Memory drove a critical process of feeding habit transformation in Chinese perch when they re-trained to eat dead prey fish. To investigate the regulatory mechanism of cAMP-response element-binding protein (CREB) signaling pathway on the memory of Chinese perch during feeding habit transformation, the phosphorylation levels of upstream signal proteins of CREB between the control group (trained once) and the experimental group (trained twice) were measured. The results illustrated that the re-training was correlated to phosphorylation of extracellular regulated protein kinase (ERK1/2) and calcium/calmodulin-dependent protein kinase II (CaMKII), and dephosphorylation of protein kinase A (PKA) of Chinese perch. Inhibition of ERK1/2-CREB pathway decreased the mRNA levels of memory-related genes ((fos-related antigen 2 (fra2), CCAAT enhancer-binding protein delta (c/ebpb), immediate-early gene zif268 (zif268), proto-oncogenes c-fos (c-fox) and synaptotagmin-IV (sytIV)) and mRNA levels of appetite-related genes (agouti-related peptide (agrp) and ghrelin), and activation of PP1-CREB pathway increased the phosphorylated levels of CREB, the mRNA levels of memory-related genes (fra2, c/ebpb, zif268, and c-fox), and the mRNA levels of appetite-related genes (pro-opiomelanocortin (pomc) and leptin) in primary brain cells of Chinese perch. The memory in Chinese perch feeding habit transformation was associated with the ERK1/2-CREB and PP1-CREB pathways, which could regulate the transcription of memory-related genes and appetite-related genes.

Indexed as

Cyclic AMP Response Element-Binding ProteinFeeding BehaviorMemoryPerchesAnimalsRNA, MessengerCyclic AMP Response Element-Binding ProteinRNA, MessengerAppetiteCREBFeeding behaviorMemorySiniperca chuatsi

Identifiers

PMID34581919
OpenAlexW3201742707

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.