Evidence map›Paper›PMID 34581827›Full record

ReviewAnalytical and bioanalytical chemistry2022

Advances in aptamer-based sensing assays for C-reactive protein.

Ming-Qing Tang, Jing Xie, Liang-Ming Rao, Ya-Jie Kan, Pei Luo, Lin-Sen Qing

Abstract readReview
PubMed Publisher
In one paragraph

Review in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Recent Advances in Aptamer-Based Applications in Cardiology.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Review
  4. Visual dual-mode aptasensor for non-small cell lung cancer exosome detection via HRP self-coupling enhanced oxidized iridium nanoparticle aggregation.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ming-Qing Tang *School of Pharmacy, Chengdu Medical College, Chengdu, 610500, Sichuan, China.
Jing Xie *School of Pharmacy, Chengdu Medical College, Chengdu, 610500, Sichuan, China.
Liang-Ming RaoShanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, 200031, China.
Ya-Jie KanSchool of Pharmacy, Chengdu Medical College, Chengdu, 610500, Sichuan, China.
Pei LuoState Key Laboratory for Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, SAR, China. pluo@must.edu.mo.
Lin-Sen QingChengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, Sichuan, China. qingls@cib.ac.cn.

Funding

Chinese Academy of Sciences (CAS) 'Light of West China' Program 2018XBZG_XBQNXZ_A_005Faculty Research Grants of Macau University of Science and Technology FRG-20-004-SKLInnovation Training Program for College Students in Sichuan Province of China S202013705121Key Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department 10Y201802
6 · The paper itself

Abstract

C-reactive protein (CRP), a non-specific acute-phase indicator of inflammation, has been widely recognized for its value in clinical diagnostic applications. With the advancement of testing technologies, there have been many reports on fast, simple, and reliable methods for CRP testing. Among these, the aptamer-based biosensors are the focus and hotspot of research for achieving high-sensitivity analysis of CRP. This review summarizes the progress of in vitro aptamer screening for CRP and the recent advances in aptamer-based CRP sensor applications, thus developing insight for the new CRP aptasensor design strategy.

Indexed as

Aptamers, NucleotideBiosensing TechniquesC-Reactive ProteinElectrochemical TechniquesHumansMicrofluidic Analytical TechniquesOptics and PhotonicsReproducibility of ResultsSELEX Aptamer TechniqueSurface Plasmon ResonanceAptamers, NucleotideC-Reactive ProteinAptamerAptasensorC-reactive proteinSELEX

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.