Evidence map›Paper›PMID 34581704›Full record

ArticleJournal of computer assisted tomography

Magnetic Resonance Elastography of the Liver: A Single-Institution Review of Cases Performed in a 5-Year Interval.

Carlos Morillo-Hernandez, Roberta Catania, Philip J Grosse, Gideon Bollino, Amir A Borhani, Alessandro Furlan

Open access · greenAbstract read
In one paragraph

Article in Journal of computer assisted tomography. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Carlos Morillo-HernandezFrom the University of Pittsburgh School of Medicine.
Roberta Catania
Philip J GrosseUniversity of Pittsburgh Clinical and Translational Science Institute, Pittsburgh, PA.
Gideon BollinoDepartment of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA.
Amir A Borhani
Alessandro FurlanDepartment of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA.
University of Pittsburgh Medical Center · USUniversity of Pittsburgh · USNorthwestern University · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
NCATS NIH HHS UL1 TR001857
6 · The paper itself

Abstract

objectiveThis study aimed to assess the diagnostic accuracy of magnetic resonance elastography (MRE) in detecting hepatic fibrosis and determining clinically relevant stiffness cutoff values per stage of fibrosis.

methodsThis retrospective study assessed 1488 hepatic MRE evaluations performed at a single institution for 5 years. Mean liver stiffness measurements were collected from 282 patients who had an MRE study within 1 year of histopathologic analysis. Areas under receiver operating characteristic curves were calculated for each stage of fibrosis with nonparametric ordinal measures of accuracy, and Youden Index was determined.

resultsMean liver stiffness measurement values were as follows: F0, 2.5± 0.55 kPa; F1, 3.1± 0.80 kPa; F2, 3.4±0.95 kPa; F3, 4.7±1.44 kPa; and F4, 7.9± 2.64 kPa. Nonparametric ordinal measures of accuracy per fibrosis stage were as follows: F0: 0.934, P < 0.001; F0-F1: 0.917, P < 0.001; F0-F2: 0.944, P < 0.001; and F0-F3: 0.941, P < 0.001. Youden Index values for fibrosis stages F2, F3, and F4 were 3.9, 4.0, and 4.5 kPa, respectively.

conclusionsMagnetic resonance elastography is an accurate diagnostic tool in assessing liver fibrosis.

Indexed as

AdultAgedAged, 80 and overDisease ProgressionElasticity Imaging TechniquesFemaleHumansImage Interpretation, Computer-AssistedLiverLiver CirrhosisMaleMiddle AgedRetrospective StudiesYoung Adult

Identifiers

PMID34581704
PMCPMC8986030
OpenAlexW3203239149

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.