ArticleAlcoholism, clinical and experimental research2021
Correlates of mild, moderate, and severe Alcohol Use Disorder among adults with problem substance use: Validity implications for DSM-5.
Article in Alcoholism, clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Therapeutic Effects of Dihydromyricetin on Wholly Alcohol-Attributed Conditions: A Systematic Review.Nutrients · 2026Pooled it
- A sex- and gender-based analysis of alcohol treatment intervention research involving youth: A methodological systematic review.PLoS medicine · 2024Pooled it
- The OPRM1 A118G G Allele Is Associated With Poorer Auditory-Verbal Learning and Memory, Executive Functions, and Working Memory in Veterans Undergoing Residential Treatment for Alcohol Use Disorder.Alcohol, clinical & experimental research · 2026Article
- Identifying dominant factors that impact hazardous alcohol use among sexual and gender minority groups.Addictive behaviors reports · 2026Article
- Substance use disorder severity is associated with sensitivity to effort-related decision-making constraints.Psychopharmacology · 2025Article
- DSM-5 Criteria for Alcohol and Cannabis Use Disorders: Are Older Adults Less Likely to Endorse Certain Criteria?International journal of environmental research and public health · 2025Article
- Considerations for understanding the neurobiology of pathological alcohol choice preference: Commentary on Perini, Karlsson, McIntyre, Heilig-"Neural correlates of choosing alcohol over palatable food reward in humans".Alcohol, clinical & experimental research · 2025Article
- Effects of intermittent theta burst to the left dorsolateral prefrontal cortex on brain volumes and neurometabolites in people with alcohol use disorder: a preliminary investigation.Frontiers in human neuroscience · 2025Article
- Examination of the mild, moderate, and severe alcohol use disorder severity indicators using a nationally representative sample.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024Article
- Regional cortical thickness recovery with extended abstinence after treatment in those with alcohol use disorder.Alcohol (Fayetteville, N.Y.) · 2024Article
- Child maltreatment and parental domestic violence and abuse, co-occurrence and the effect on lifetime outcomes in the Avon Longitudinal Study of Parents and Children (ALSPAC).SSM - population health · 2023Article
- Diagnostic Criteria for Identifying Individuals at High Risk of Progression From Mild or Moderate to Severe Alcohol Use Disorder.JAMA network open · 2023Article
- Article
- Construct validity of DSM-5 cannabis use disorder diagnosis and severity levels in adults with problematic substance use.Journal of psychiatric research · 2022Article
- Validity of the DSM-5 tobacco use disorder diagnostics in adults with problematic substance use.Drug and alcohol dependence · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe DSM-5 definition of alcohol use disorder (AUD) has been well validated, but information is lacking on the extent to which alcohol use, comorbidity, and impairment are associated with the 3 DSM-5-defined AUD severity levels: mild, moderate, and severe. This study examined clinical and functional characteristics as predictors (validators) of these severity levels.
methodsParticipants aged ≥18 years reporting current problem substance use (N = 588) were recruited between 2016 and 2019 and assessed for DSM-5 AUD and a set of potential validators: indicators of alcohol use severity (i.e., craving, binge drinking frequency, problematic use, and harmful drinking), psychiatric disorders, and functional impairment. Multinomial logistic regression models examined the association between the predictors and the 3 AUD severity levels (mild, moderate, and severe) vs the reference group, no AUD, controlling for sociodemographic characteristics and other substance use.
resultsAll alcohol use validators were associated with a greater likelihood of all 3 AUD severity levels compared with the no-AUD group. However, psychiatric disorders were associated only with severe AUD and participants with major depression (aOR = 2.44), posttraumatic stress disorder (aOR = 1.65), borderline personality disorder (aOR = 1.99), and antisocial personality disorder (aOR = 1.78) had a greater likelihood of severe AUD than the no-AUD group. Functioning validators were also associated only with severe AUD and participants with social (aOR = 1.87), physical (aOR = 1.62), or mental (aOR = 1.84) impairment had a greater likelihood of severe AUD than the no-AUD group. Many alcohol-related, psychiatric, and functioning validators were associated with greater odds of severe AUD than mild or moderate AUD.
conclusionThis study supports the criterion validity of the DSM-5 tri-categorical measure of AUD. Specifically, results fully supported the validity of severe AUD by its associations with all predictors, whereas the validity of mild and moderate AUD was supported only by alcohol use predictor variables. Findings suggest the value of using severity-specific interventions utilizing the DSM-5 AUD.
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