Evidence map›Paper›PMID 34581374›Full record

ArticleLab on a chip2021

A bioinspired, passive microfluidic lobe filtration system.

Andrew S Clark, Adriana San-Miguel

Open access · greenAbstract read
In one paragraph

Article in Lab on a chip, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andrew S ClarkDepartment of Chemical & Biomolecular Engineering, North Carolina State University, Raleigh, NC, USA. asanmig@ncsu.edu.
Adriana San-MiguelDepartment of Chemical & Biomolecular Engineering, North Carolina State University, Raleigh, NC, USA. asanmig@ncsu.edu.ORCID 0000-0003-0172-2163
North Carolina State University · US

Funding

A platform for in vivo lifelong tracking of aging genes and lifespan prediction under precise environments in C. elegans.R21AG059099 · NIA · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI FLORES, KEVIN, SAN MIGUEL, ADRIANA · 2019 to 2020
$401k
NIA NIH HHS R21 AG059099US National Science Foundation IOS 1838314
6 · The paper itself

Abstract

Size-based microfluidic filtration systems can be affected by clogging, which prevents their use in high-throughput and continuous applications. To address these concerns, we have developed two microfluidic lobe filters bioinspired by the filtration mechanism of two species of manta ray. These chips enable filtration of particles around 10-30 μm with precise control and high throughput by using two arrays of equally spaced filter lobes. For each filter design, we investigated multiple inlet flow rates and particle sizes to identify successful operational parameters. Filtration efficiency increases with fluid flow rate, suggesting that particle inertial effects play a key role in lobe filter separation. Microparticle filtration efficiencies up to 99% were obtainable with inlet flow rates of 20 mL min

Indexed as

Microfluidic Analytical TechniquesMicrofluidicsFiltrationParticle Size

Identifiers

PMID34581374
PMCPMC8486309
OpenAlexW3187197228

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.