Trial reportJournal of the American Heart Association2021
Incidence and Outcomes of Infective Endocarditis After Transcatheter or Surgical Aortic Valve Replacement.
Trial report in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Prevalence of healthcare-associated infections in developing and developed countries: a systematic review.BMC infectious diseases · 2026Pooled it
- Contemporary Management of Aortic Stenosis: Timing of Intervention and Lifetime Valve Management.European journal of clinical investigation · 2026Review
- Changing Patterns in Infective Endocarditis: A Contemporary Epidemiological Perspective.Pathogens (Basel, Switzerland) · 2026Review
- Managing Transcatheter Aortic Valve Failure.Structural heart : the journal of the Heart Team · 2026Review
- A Reproducible Post-Valve-Replacement EHR Cohort for Comparative AI Studies.Diagnostics (Basel, Switzerland) · 2026Article
- Current Advances in Epidemiology, Diagnosis, and Management of TAVR-Associated Infective Endocarditis: A Narrative Review.Reviews in cardiovascular medicine · 2026Review
- Emerging insights into infective endocarditis in the era of transcatheter aortic valve implantation.Frontiers in cellular and infection microbiology · 2026Review
- Clinical presentation, microbiological profile, and management challenges of infective endocarditis: a retrospective study from a high volume cardiac centre in Pakistan.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025Article
- Necessity of dental restoration before heart valve replacement: a cross-sectional study of a historical cohort.Clinical oral investigations · 2025Article
- Incidence and Early Mortality of Prosthetic Valve Endocarditis in Patients Undergoing TAVI Compared to SAVR: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Surgical management is associated with improved survival for endocarditis after transcatheter aortic valve replacement.Annals of cardiothoracic surgery · 2025Article
- What Are SAVR Indications in the TAVI Era?Journal of clinical medicine · 2025Review
- Diabetes and calcific aortic valve disease: controversy of clinical outcomes in diabetes after aortic valve replacement.Frontiers in endocrinology · 2025Review
- Mitral valve repair and replacement in infectious endocarditis: a systematic review and meta-analysis of clinical outcome.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024Review
- Infection of Transcatheter Valvular Devices.Current cardiology reports · 2024Review
- Ten-Year Experience with a Transapical Approach for Transcatheter Aortic and Mitral Valve Implantation.Journal of cardiovascular development and disease · 2024Article
- Midterm results after aortic valve neocuspidization.JTCVS techniques · 2024Article
- Aortic Stenosis Management in Patients With Acute Hip Fracture.JACC. Advances · 2024Review
- Review
- Infective endocarditis after isolated aortic valve replacement: comparison between catheter-interventional and surgical valve replacement.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Data comparing the frequency and outcomes of infective endocarditis (IE) after transcatheter (TAVR) to surgical aortic valve replacement (SAVR) are scarce. The objective of this study is to compare the incidence and outcomes of IE after TAVR using a supra-annular, self-expanding platform (CoreValve and Evolut) to SAVR. Methods and Results Data of 3 randomized clinical trials comparing TAVR to SAVR and a prospective continued TAVR access study were pooled. IE was defined on the basis of the modified Duke criteria. The cumulative incidence of IE was determined by modeling the cause-specific hazard. Estimates of all-cause mortality were calculated by means of the Kaplan-Meier method. Outcomes are reported for the valve-implant cohort. During a mean follow-up time of 2.17±1.51 years, 12 (0.5%) of 2249 patients undergoing TAVR and 21 (1.1%) of 1828 patients undergoing SAVR developed IE. Patients with IE more frequently had diabetes mellitus than those without (57.6% versus 34.2%;
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.