Evidence map›Paper›PMID 34581027›Full record

ArticlePediatric obesity2022

Age-dependent association of obesity with COVID-19 severity in paediatric patients.

Benedict Vincent Guzman, Brian Elbel, Melanie Jay, Mary Jo Messito, Silvia Curado

Open access · bronzeAbstract read
In one paragraph

Article in Pediatric obesity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Benedict Vincent GuzmanNYU Langone Comprehensive Program on Obesity, NYU Grossman School of Medicine, New York, New York, USA.ORCID 0000-0002-2791-1491
Brian ElbelNYU Langone Comprehensive Program on Obesity, NYU Grossman School of Medicine, New York, New York, USA.
Melanie JayNYU Langone Comprehensive Program on Obesity, NYU Grossman School of Medicine, New York, New York, USA.
Mary Jo MessitoNYU Langone Comprehensive Program on Obesity, NYU Grossman School of Medicine, New York, New York, USA.ORCID 0000-0001-5328-0593
Silvia CuradoNYU Langone Comprehensive Program on Obesity, NYU Grossman School of Medicine, New York, New York, USA.
New York University · USBellevue Hospital Center · USWagner College · US

Funding

Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
NIDDK NIH HHS P30 DK092926NIDDK NIH HHS P30 DK111022
6 · The paper itself

Abstract

backgroundLimited research has addressed the obesity-COVID-19 severity association in paediatric patients.

objectiveTo determine whether obesity is an independent risk factor for COVID-19 severity in paediatric patients and whether age modifies this association.

methodsSARS-CoV-2-positive patients at NYU Langone Health from 1 March 2020 to 3 January 2021 aged 0-21 years with available anthropometric measurements: weight, length/height and/or body mass index (BMI). Modified log-Poisson models were utilized for the analysis. Main outcomes were 1) hospitalization and 2) critical illness (intensive care unit [ICU] admission).

resultsOne hundred and fifteen of four hundred and ninety-four (23.3%) patients had obesity. Obesity was an independent risk factor for critical illness (adjusted risk ratio [ARR] 2.02, 95% CI 1.17 to 3.48). This association was modified by age, with obesity related to a greater risk for critical illness in adolescents (13-21 years) [ARR 3.09, 95% CI 1.48 to 6.47], but not in children (0-12 years). Obesity was not an independent risk factor for hospitalization for any age.

conclusionObesity was an independent risk factor for critical illness in paediatric patients, and this association was modified by age, with obesity related to a greater risk for critical illness in adolescents, but not in children. These findings are crucial for patient risk stratification and care.

Indexed as

COVID-19AdolescentAdultBody Mass IndexChildChild, PreschoolHospitalizationHumansInfantInfant, NewbornObesityRisk FactorsSARS-CoV-2Severity of Illness IndexYoung Adultadolescent health/medicineCOVID-19obesitypaediatric obesitypaediatrics

Identifiers

PMID34581027
PMCPMC8646488
OpenAlexW3204219477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.