Evidence map›Paper›PMID 34581018›Full record

ArticleThoracic cancer2021

Increased carbohydrate antigen 19-9 expression in a thymic neuroendocrine tumor.

Yuki Shimizu, Shintaro Kanda, Toshirou Fukushima, Takashi Kobayashi, Ryoichi Kondo, Tomonobu Koizumi

Open access · goldAbstract readCase Reports
In one paragraph

Article in Thoracic cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yuki ShimizuDepartment of Hematology and Medical Oncology, Division of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan.
Shintaro KandaDepartment of Hematology and Medical Oncology, Division of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan.ORCID 0000-0001-7864-3928
Toshirou FukushimaDepartment of Hematology and Medical Oncology, Division of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan.
Takashi KobayashiDepartment of Hematology and Medical Oncology, Division of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan.
Ryoichi KondoDepartment of Thoracic Surgery, National Hospital Organization Matsumoto Medical Center, Matsumoto, Japan.
Tomonobu KoizumiDepartment of Hematology and Medical Oncology, Division of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan.ORCID 0000-0002-5182-0960
Shinshu University · JPNational Hospital Organization · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we report a case of carbohydrate antigen (CA) 19-9-producing mediastinal neuroendocrine tumor (NET) (atypical carcinoid). A 54-year-old woman with no specific relevant medical history was referred to our hospital because of increased CA19-9 (95.3 U/ml) detected on health screening. Chest computed tomography (CT) revealed an anterior mediastinal mass without localized lymphadenopathy. Thoracic surgery was performed and the histopathological diagnosis was thymic CA19-9-positive NET. The patient developed mediastinal lymph node metastasis at 1 year (CA19-9: 413 U/ml) and multiple bone metastases 4 years (CA19-9: 2303 U/ml) after surgery. Increased CA19-9 levels paralleled the clinical courses of relapse. To our knowledge, this is the first report of CA19-9-producing thymic NET.

Indexed as

Lymphatic MetastasisBiomarkers, TumorBone NeoplasmsCA-19-9 AntigenFemaleHumansMediastinal NeoplasmsMiddle AgedNeuroendocrine TumorsThymus NeoplasmsBiomarkers, TumorCA-19-9 Antigenimmunohistochemical stainneuroendocrine tumorthymic carcinoidtumor marker

Identifiers

PMID34581018
PMCPMC8563154
OpenAlexW3203522947

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.