Evidence map›Paper›PMID 34580981›Full record

ArticleChemphyschem : a European journal of chemical physics and physical chemistry2021

A Versatile Compact Parahydrogen Membrane Reactor.

Patrick M TomHon, Suyong Han, Sören Lehmkuhl, Stephan Appelt, Eduard Y Chekmenev, Milad Abolhasani, Thomas Theis

Abstract read
In one paragraph

Article in Chemphyschem : a European journal of chemical physics and physical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. AutomatedAnalytical chemistry · 2026
    Article
  2. Article
  3. Toward Ultra-High-Quality-Factor Wireless Masing Magnetic Resonance Sensing.Angewandte Chemie (International ed. in English) · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
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  10. Review
  11. Article
  12. Article
  13. Article
  14. RapidAnalytical chemistry · 2022
    Article
  15. Article
  16. Order-UnityChemphyschem : a European journal of chemical physics and physical chemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Patrick M TomHonDepartment of Chemistry, North Carolina State University, Raleigh, NC, 27695, USA.
Suyong HanDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC, 27606, USA.
Sören LehmkuhlDepartment of Chemistry, North Carolina State University, Raleigh, NC, 27695, USA.
Stephan AppeltCentral Institute for Engineering, Electronics and Analytics - Electronic Systems (ZEA-2), Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
Eduard Y ChekmenevDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, MI, 48202, USA.
Milad AbolhasaniDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC, 27606, USA.
Thomas TheisDepartment of Chemistry, North Carolina State University, Raleigh, NC, 27695, USA.

Funding

Molecular MRI of Brain Metabolism Enabled by Long-Lived Spin StatesR01EB029829 · NIBIB · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI THEIS, THOMAS · 2020 to 2020
$807k
Molecular imaging with a hyperpolarized Vitamin ShotR21EB025313 · NIBIB · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI THEIS, THOMAS · 2018 to 2019
$661k
Magnetic Resonance Spectroscopy and Molecular Imaging of Metabolic Pathways in CancerR21CA220137 · NCI · WAYNE STATE UNIVERSITY · PI CHEKMENEV, EDUARD · 2017 to 2019
$390k
Mallinckrodt FoundationNational Science Foundation NSF CHE-1904780NCI NIH HHS NCI 1R21CA220137NCI NIH HHS R21 CA220137NIBIB NIH HHS R01 EB029829NIBIB NIH HHS R21 EB025313NIH HHSNIH HHS NIH R01EB029829NIH HHS NIH R21-EB025313North Carolina Biotechnology Center
6 · The paper itself

Abstract

We introduce a Spin Transfer Automated Reactor (STAR) that produces continuous parahydrogen induced polarization (PHIP), which is stable for hours to days. We use the PHIP variant called signal amplification by reversible exchange (SABRE), which is particularly well suited to produce continuous hyperpolarization. The STAR is operated in conjunction with benchtop (1.1 T) and high field (9.4 T) NMR magnets, highlighting the versatility of this system to operate with any NMR or MRI system. The STAR uses semipermeable membranes to efficiently deliver parahydrogen into solutions at nano to milli Tesla fields, which enables

Indexed as

Magnetic Resonance ImagingMagnetic Resonance SpectroscopyfluidicshyperpolarizationNMRparahydrogenRASER

Identifiers

PMID34580981
PMCPMC8785414

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.