Evidence map›Paper›PMID 34580967›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Versatile Polymer Nanocapsules via Redox Competition.

Jiajing Zhou, Ming Xu, Zhicheng Jin, Raina M Borum, Nicole Avakyan, Yong Cheng, Wonjun Yim, Tengyu He, Jingcheng Zhou, Zhuohong Wu and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Peptidic Sulfhydryl for Interfacing Nanocrystals and Subsequent Sensing of SARS-CoV-2 Protease.Chemistry of materials : a publication of the American Chemical Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Jiajing ZhouDepartment of NanoEngineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.ORCID 0000-0001-5203-4737
Ming XuDepartment of NanoEngineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.ORCID 0000-0002-6998-8462
Zhicheng JinDepartment of NanoEngineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Raina M BorumDepartment of NanoEngineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Nicole AvakyanDepartment of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, California, 92093, USA.
Yong ChengDepartment of NanoEngineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Wonjun YimMaterials Science and Engineering Program, University of California San Diego, 9500 Gilman Drive, La Jolla, California, 92093, USA.ORCID 0000-0002-0242-7898
Tengyu HeMaterials Science and Engineering Program, University of California San Diego, 9500 Gilman Drive, La Jolla, California, 92093, USA.ORCID 0000-0002-6767-4849
Jingcheng ZhouDepartment of NanoEngineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Zhuohong WuDepartment of NanoEngineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Yash MantriDepartment of Bioengineering, University of California San Diego, 9500 Gilman Drive, La Jolla, California, 92093, USA.
Jesse V JokerstDepartment of NanoEngineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.ORCID 0000-0003-2829-6408
University of California San Diego · US

Funding

Therapeutic Drug Monitoring with a Wearable Ultrasound-based SensorDP2HL137187 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2016 to 2019
$2.7M
Cancer Researchers in Nanotechnology (CRIN)T32CA153915 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KUMMEL, ANDREW CLYDE, ZHANG, DONG-ER · 2017 to 2021
$994k
Vevo LAZR Photoacoustic Imaging SystemS10OD021821 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HALL, DAVID J · 2016 to 2016
$594k
MANTA ViewSizer 3011 Nanoparticle Characterization SystemS10OD023555 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2018 to 2018
$137k
National Science Foundation 1845683National Science Foundation DMR-2004558National Science Foundation DMR-2011924National Science Foundation ECCS-1542148NCI NIH HHS T32 CA153915NHLBI NIH HHS DP2 HL137187NIH HHS DP2 HL137187NIH HHS S10 OD021821NIH HHS S10 OD023555
6 · The paper itself

Abstract

Polymer nanocapsules have demonstrated significant value in materials science and biomedical technology, but require complicated and time-consuming synthetic steps. We report here the facile synthesis of monodisperse polymer nanocapsules via a redox-mediated kinetic strategy from two simple molecules: dopamine and benzene-1,4-dithiol (BDT). Specifically, BDT forms core templates and modulates the oxidation kinetics of dopamine into polydopamine (PDA) shells. These uniform nanoparticles can be tuned between ≈70 and 200 nm because the core diameter directly depends on BDT while the shell thickness depends on dopamine. The supramolecular core can then rapidly disassemble in organic solvents to produce PDA nanocapsules. Such nanocapsules exhibit enhanced physicochemical performance (e.g., loading capacity, photothermal transduction, and anti-oxidation) versus their solid counterparts. Particularly, this method enables a straightforward encapsulation of functional nanoparticles providing opportunities for designing complex nanostructures such as yolk-shell nanoparticles.

Indexed as

DopamineIndolesMolecular StructureNanocapsulesOxidation-ReductionParticle SizePolymersSulfhydryl Compounds1,4-benzenedithiolDopamineIndolesNanocapsulespolydopaminePolymersSulfhydryl Compoundsfunctional self-assemblynanocapsulespolydopaminesupramolecular chemistrytheranostic probes

Identifiers

PMID34580967
PMCPMC8629958
OpenAlexW3201722146

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.