Evidence map›Paper›PMID 34580843›Full record

ArticleReproductive sciences (Thousand Oaks, Calif.)2022

High Maternal Serum Estradiol in First Trimester of Multiple Pregnancy Contributes to Small for Gestational Age via DNMT1-Mediated CDKN1C Upregulation.

Xiao-Ling Hu, Shuai Shi, Ning-Ning Hou, Ye Meng, Miao Li, Ai-Xia Liu, Yong-Chao Lu, Jing-Yi Li, Jian-Zhong Sheng, Yi-Min Zhu and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Reproductive sciences (Thousand Oaks, Calif.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Xiao-Ling HuDepartment of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, 1 Xueshi Rd, Hangzhou, 310006, Zhejiang, China.
Shuai ShiDepartment of Pathology and Pathophysiology, School of Medicine, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Ning-Ning HouDepartment of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, 1 Xueshi Rd, Hangzhou, 310006, Zhejiang, China.
Ye MengDepartment of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, 1 Xueshi Rd, Hangzhou, 310006, Zhejiang, China.
Miao LiDepartment of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, 1 Xueshi Rd, Hangzhou, 310006, Zhejiang, China.
Ai-Xia LiuDepartment of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, 1 Xueshi Rd, Hangzhou, 310006, Zhejiang, China.
Yong-Chao LuDepartment of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, 1 Xueshi Rd, Hangzhou, 310006, Zhejiang, China.
Jing-Yi LiDepartment of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, 1 Xueshi Rd, Hangzhou, 310006, Zhejiang, China.
Jian-Zhong ShengDepartment of Pathology and Pathophysiology, School of Medicine, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Yi-Min ZhuDepartment of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, 1 Xueshi Rd, Hangzhou, 310006, Zhejiang, China. zhuyim@zju.edu.cn.ORCID 0000-0002-9667-3677
He-Feng HuangDepartment of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, 1 Xueshi Rd, Hangzhou, 310006, Zhejiang, China. hhf57@zju.edu.cn.ORCID 0000-0002-0195-985X
Women's Hospital, School of Medicine, Zhejiang University · CNZhejiang University · CNMinistry of Education · NZMinistry of Education · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High maternal serum estradiol (E

Indexed as

Infant, Small for Gestational AgeCyclin-Dependent Kinase Inhibitor p57DNA (Cytosine-5-)-Methyltransferase 1EstradiolFemaleFetal Growth RetardationGestational AgeHumansInfant, NewbornPregnancyPregnancy, MultiplePregnancy Trimester, FirstUp-RegulationCDKN1C protein, humanCyclin-Dependent Kinase Inhibitor p57DNA (Cytosine-5-)-Methyltransferase 1DNMT1 protein, humanEstradiolCDKN1CEstradiolEstrogen response elementsLow birth weightSmall for gestational age

Identifiers

PMID34580843
PMCPMC8907102
OpenAlexW3201861214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.