Evidence map›Paper›PMID 34580197›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

IP

Scott A Tiscione, Maria Casas, Jonathan D Horvath, Vincent Lam, Keiko Hino, Daniel S Ory, L Fernando Santana, Sergi Simó, Rose E Dixon, Eamonn J Dickson

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Mitochondrial CaJournal of cellular physiology · 2025
    Review
  3. Article
  4. Unifying biology of neurodegeneration in lysosomal storage diseases.Journal of inherited metabolic disease · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. NPC1-dependent alterations in KNature communications · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. CaAdvances in experimental medicine and biology · 2023
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. IPContact (Thousand Oaks (Ventura County, Calif.))
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Scott A TiscioneDepartment of Physiology and Membrane Biology, University of California, Davis, CA 95616.
Maria CasasDepartment of Physiology and Membrane Biology, University of California, Davis, CA 95616.ORCID 0000-0002-5246-8874
Jonathan D HorvathDepartment of Physiology and Membrane Biology, University of California, Davis, CA 95616.
Vincent LamDepartment of Physiology and Membrane Biology, University of California, Davis, CA 95616.
Keiko HinoDepartment of Cell Biology and Human Anatomy, University of California, Davis, CA 95616.
Daniel S OryDepartment of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
L Fernando SantanaDepartment of Physiology and Membrane Biology, University of California, Davis, CA 95616.ORCID 0000-0002-4297-8029
Sergi SimóDepartment of Cell Biology and Human Anatomy, University of California, Davis, CA 95616.ORCID 0000-0002-8344-0313
Rose E DixonDepartment of Physiology and Membrane Biology, University of California, Davis, CA 95616.ORCID 0000-0003-0655-690X
Eamonn J DicksonDepartment of Physiology and Membrane Biology, University of California, Davis, CA 95616; ejdickson@ucdavis.edu.ORCID 0000-0001-8619-7630
University of California, Davis · USWashington University in St. Louis · US

Funding

Molecular choreography of CaV1.2 channels in the aging myocardiumR01AG063796 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Rose Ellen Dixon · 2019 to 2026
$3.1M
Neuronal Kv2.1 Potassium Channels as Organizers of Somatic L-Type Calcium Channel MicrodomainsR01NS114210 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DICKSON, EAMONN JAMES, SANTANA, LUIS F · 2020 to 2024
$2.3M
Predoctoral Training in Pharmacological SciencesT32GM099608 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2012 to 2021
$2.2M
Tuning L-Type Ca Channel Activity in Arterial Smooth Muscle by Kv Channel-Mediated ClusteringR01HL144071 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SANTANA, LUIS F, TRIMMER, JAMES S · 2018 to 2021
$2.0M
Regulation of hippocampal morphogenesis and homeostasis by the E3 ubiquitin ligase CRL5R01NS109176 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SIMO, SERGI · 2019 to 2023
$1.7M
Membrane contact sites regulate cellular excitabilityR01GM127513 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DICKSON, EAMONN JAMES · 2019 to 2023
$1.6M
NHLBI NIH HHS R01 HL144071NIA NIH HHS R01 AG063796NIGMS NIH HHS R01 GM127513NIGMS NIH HHS T32 GM099608NINDS NIH HHS R01 NS109176NINDS NIH HHS R01 NS114210
6 · The paper itself

Abstract

Ca

Indexed as

AnimalsBiological TransportCalciumCell DeathCell LineCholesterolEndoplasmic ReticulumFemaleHumansInositol 1,4,5-Trisphosphate ReceptorsLysosomesMaleMembrane GlycoproteinsMiceMitochondriaNeurodegenerative DiseasesCalciumCholesterolInositol 1,4,5-Trisphosphate ReceptorsItpr1 protein, mouseMembrane GlycoproteinsPresenilin-1calciumGPCRIP3RneurodegenerationNPC1

Identifiers

PMID34580197
PMCPMC8501836
OpenAlexW3202644178

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.