Evidence map›Paper›PMID 34580176›Full record

ArticleLife science alliance2021

Functional and metabolic fitness of human CD4

Lisa Holthaus, Virag Sharma, Daniel Brandt, Anette-Gabriele Ziegler, Martin Jastroch, Ezio Bonifacio

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Lisa HolthausInstitute for Diabetes and Obesity, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany.ORCID 0000-0002-6082-3944
Virag SharmaGerman Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.ORCID 0000-0003-4086-4105
Daniel BrandtInstitute for Diabetes and Obesity, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Anette-Gabriele ZieglerInstitute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Martin JastrochInstitute for Diabetes and Obesity, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Ezio BonifacioInstitute for Diabetes and Obesity, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany ezio.bonifacio@tu-dresden.de.ORCID 0000-0002-8704-4713
Helmholtz Zentrum München · DEDeutsches Diabetes-Zentrum e.V. · DEStockholm University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human CD4

Indexed as

2',5'-Oligoadenylate SynthetaseAdultAntioxidantsBlood DonorsCD4-Positive T-LymphocytesCell ProliferationCells, CulturedCytokinesDown-RegulationGlucoseGlycolysisHumansLymphocyte ActivationMaleMitochondriaOxidative Phosphorylation2',5'-Oligoadenylate SynthetaseAntioxidantsCytokinesGlucoseResveratrol

Identifiers

PMID34580176
PMCPMC8500231
OpenAlexW3201941650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.