Evidence map›Paper›PMID 34580065›Full record

ArticleBJGP open2021

Transient elastography in patients at risk of liver fibrosis in primary care: a follow-up study over 54 months.

Tina Reinson, Christopher D Byrne, Janisha Patel, Magdy El-Gohary, Michael Moore

Open access · goldAbstract read
In one paragraph

Article in BJGP open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Tina ReinsonResearcher, Primary Care, Population Sciences and Medical Education, Faculty of Medicine, University of Southampton, Southampton, UK t.reinson@soton.ac.uk.
Christopher D ByrneProfessor of Endocrinology and Metabolism, Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.
Janisha PatelConsultant Hepatologist, Department of Gastroenterology and Hepatology, University Hospital Southampton, Southampton, UK.
Magdy El-GoharyGP, Shirley Health Partnership, Southampton, UK.
Michael MooreProfessor of Primary Health Care Research, Primary Care, Population Sciences and Medical Education, Faculty of Medicine, University of Southampton, Southampton, UK.
Primary Health Care · QACommunity Health Partnership · USUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Southampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiver fibrosis assessment services using transient elastography are growing in primary care. These services identify patients requiring specialist referral for liver fibrosis, and provide an opportunity for recommending lifestyle change. However, there are uncertainties regarding service design, effectiveness of advice given, and frequency of follow-up.

aimTo assess the following: (a) effectiveness of standard care lifestyle advice for weight management and alcohol consumption; (b) uptake for liver rescan; and (c) usefulness of a 4.5-year time interval of rescanning in monitoring progression of liver fibrosis. DESIGN &

settingAnalysis of patient outcomes 4.5 years after the first 'liver service' attendance that included transient elastography in five GP practices in Southampton, UK.

methodOutcomes included weight, alcohol consumption, rescan uptake, time interval between scans, and change in liver fibrosis stage.

resultsA total of 401 participants were recontacted. Mean standard deviation (± SD) weight loss was 1.2 kg±8.4 kg (

conclusionRescan recall attendance and adherence to lifestyle changes needs improving. Optimum time interval between scans remains uncertain. After a mean interval of 53.6 months between scans, and with no specific predictors indicated, a substantial minority (18.7%) experienced a deterioration in fibrosis grade.

Indexed as

early diagnosisgeneral practiceliver diseasesmass screeningprimary healthcarerisk reduction behaviour

Identifiers

PMID34580065
PMCPMC9447304
OpenAlexW3201970257

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.