Evidence map›Paper›PMID 34579985›Full record

ArticleAmerican journal of preventive medicine2021

Severe Maternal Morbidity and Maternal Mortality in Women With Intellectual and Developmental Disabilities.

Monika Mitra, Ilhom Akobirshoev, Anne Valentine, Hilary K Brown, Tiffany A Moore Simas

Open access · greenAbstract read
In one paragraph

Article in American journal of preventive medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Functional status of women with and without potentially life-threatening maternal conditions after 6 months postpartum: A cohort study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Monika MitraThe Lurie Institute for Disability Policy, Brandeis University, Waltham, Massachusetts. Electronic address: mmitra@brandeis.edu.
Ilhom AkobirshoevThe Lurie Institute for Disability Policy, Brandeis University, Waltham, Massachusetts.
Anne ValentineThe Lurie Institute for Disability Policy, Brandeis University, Waltham, Massachusetts.
Hilary K BrownDepartment of Health and Society, University of Toronto Scarborough, Toronto, Ontario, Canada.
Tiffany A Moore SimasDepartment of Obstetrics and Gynecology, University of Massachusetts Medical School, Worcester, Massachusetts.
Brandeis University · USUniversity of Massachusetts Chan Medical School · USUniversity of Toronto · CA

Funding

Pregnancy experiences of women with IDD: Family caregiver perspectivesR01HD082105 · NICHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MITRA, MONIKA, PARISH, SUSAN L. · 2015 to 2019
$2.8M
NICHD NIH HHS R01 HD082105
6 · The paper itself

Abstract

introductionDespite increased attention on severe maternal morbidity and maternal mortality, scant research exists on adverse maternal outcomes in women with disabilities. This study compares the rates of severe maternal morbidity and maternal mortality in women with and without intellectual and developmental disabilities.

methodsThis study used 2004-2017 Healthcare Cost and Utilization Project Nationwide Inpatient Sample data. Analyses were conducted in 2019‒2020. The risk of severe maternal morbidity with and without blood transfusion and maternal mortality during delivery among women with and without intellectual and developmental disabilities were compared using modified Poisson regression analysis.

resultsThis study identified 32,324 deliveries to women with intellectual and developmental disabilities. Per 10,000 deliveries, 566 deliveries with severe maternal morbidity occurred in women with intellectual and developmental disabilities compared with 239 in women without intellectual and developmental disabilities. Women with intellectual and developmental disabilities had greater risk of both severe maternal morbidity (risk ratio=2.36, 95% CI=2.06, 2.69) and nontransfusion severe maternal morbidity (risk ratio=2.95, 95% CI=2.42, 3.61) in unadjusted analyses, which was mitigated in adjusted analyses for sociodemographic characteristics (risk ratio=1.74, 95% CI=1.47, 2.06; risk ratio=1.85, 95% CI=1.42, 2.41) and the expanded obstetric comorbidity index (risk ratio=1.23, 95% CI=1.04, 1.44; risk ratio=1.31, 95% CI=1.02, 1.68). The unadjusted incidence of maternal mortality in women with intellectual and developmental disabilities was 284 per 100,000 deliveries, nearly 4-fold higher than in women without intellectual and developmental disabilities (69 per 100,000 deliveries; risk ratio=4.07, 95% CI=2.04, 8.12), and the risk remained almost 3-fold higher after adjustment for sociodemographic characteristics (risk ratio=2.86, 95% CI=1.30, 6.29) and the expanded obstetric comorbidity index (risk ratio=2.30, 95% CI=1.05, 5.29).

conclusionsWomen with intellectual and developmental disabilities are at increased risk of severe maternal morbidity and maternal mortality. These findings underscore the need for enhanced monitoring of the needs and maternal outcomes of women with intellectual and developmental disabilities in efforts to improve maternal health.

Indexed as

Persons with DisabilitiesPregnancy ComplicationsChildDevelopmental DisabilitiesFemaleHumansIncidenceMaternal MortalityOdds RatioPregnancy

Identifiers

PMID34579985
PMCPMC8608722
OpenAlexW3203144398

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.