Evidence map›Paper›PMID 34579892›Full record

ReviewMaterials science & engineering. C, Materials for biological applications2021

Electrospun nanofiber scaffold for vascular tissue engineering.

Alex P Rickel, Xiajun Deng, Daniel Engebretson, Zhongkui Hong

Open access · greenAbstract readReview
In one paragraph

Review in Materials science & engineering. C, Materials for biological applications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 142 citations in OpenAlex.

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  6. ProlongedACS omega · 2026
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alex P RickelThe Department of Biomedical Engineering, The University of South Dakota, Sioux Falls, SD 57107, United States of America.
Xiajun DengThe Department of Biomedical Engineering, The University of South Dakota, Sioux Falls, SD 57107, United States of America.
Daniel EngebretsonThe Department of Biomedical Engineering, The University of South Dakota, Sioux Falls, SD 57107, United States of America.
Zhongkui HongThe Department of Biomedical Engineering, The University of South Dakota, Sioux Falls, SD 57107, United States of America. Electronic address: Zhongkui.Hong@usd.edu.
University of South Dakota · US

Funding

Mechanical Response and Cytoskeletal Rearrangement Following Interrupted Cholesterol Metabolism in Vascular Smooth Muscle CellR15HL147214 · NHLBI · UNIVERSITY OF SOUTH DAKOTA · PI HONG, ZHONGKUI · 2020 to 2020
$429k
NHLBI NIH HHS R15 HL147214
6 · The paper itself

Abstract

Due to the prevalence of cardiovascular diseases, there is a large need for small diameter vascular grafts that cannot be fulfilled using autologous vessels. Although medium to large diameter synthetic vessels are in use, no suitable small diameter vascular graft has been developed due to the unique dynamic environment that exists in small vessels. To achieve long term patency, a successful tissue engineered vascular graft would need to closely match the mechanical properties of native tissue, be non-thrombotic and non-immunogenic, and elicit the proper healing response and undergo remodeling to incorporate into the native vasculature. Electrospinning presents a promising approach to the development of a suitable tissue engineered vascular graft. This review provides a comprehensive overview of the different polymers, techniques, and functionalization approaches that have been used to develop an electrospun tissue engineered vascular graft.

Indexed as

BioprosthesisNanofibersVascular GraftingBlood Vessel ProsthesisTissue EngineeringTissue ScaffoldsElectrospinningScaffoldVascular tissue engineering

Identifiers

PMID34579892
PMCPMC8486306
OpenAlexW3194749261

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.