ArticleBMC pregnancy and childbirth2021
Neutrophil-lymphocyte ratio for the prediction of histological chorioamnionitis in cases of preterm premature rupture of membranes: a case-control study.
Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 35 citations in OpenAlex.
- The neutrophil-to-lymphocyte ratio: a marker for microbial invasion of the amniotic cavity in preterm prelabor rupture of membranes.Obstetrics & gynecology science · 2026Article
- Physical examination-indicated repeat cerclage in singleton pregnancies: a retrospective cohort study.BMC pregnancy and childbirth · 2026Article
- Predictive Value of Neutrophils, Lymphocytes, Platelets, Neutrophil-Lymphocyte Ratio (NLR), and Platelets-Lymphocyte Ratio (PLR) in Preterm Labor: Single and Combined Indices.Obstetrics and gynecology international · 2026Article
- Development and Validation of a Nomogram Model for Predicting Chorioamnionitis in Patients with Term Premature Rupture of Membranes.International journal of women's health · 2026Article
- Systemic immune-inflammation index predicts acute histologic chorioamnionitis pathologic staging and neonatal respiratory distress syndrome in women with preterm premature rupture of membranes: a retrospective cohort study.BMC pregnancy and childbirth · 2025Article
- Inflammatory Indices and Preterm Delivery: A New Horizon in Obstetric Risk Assessment.Diagnostics (Basel, Switzerland) · 2025Article
- Predictive value of the neutrophil-to-lymphocyte ratio for epidural labor analgesia-associated intrapartum fever: a retrospective single-center study.BMC anesthesiology · 2025Article
- Predictive potential of various plasma inflammation-, angiogenesis-, and extracellular matrix remodeling-associated mediators for intra-amniotic inflammation and/or microbial invasion of the amniotic cavity in preterm labor.Archives of gynecology and obstetrics · 2024Article
- Association Analysis Between Maternal Neutrophil Ratio and the Risk of Histological Chorioamnionitis in Pregnant Women with Premature Rupture of Membranes in Late Pregnancy.International journal of general medicine · 2024Article
- Physical Examination-Indicated Cerclage in Singleton and Twin Pregnancies and Risk Factors for Predicting Preterm Birth < 28 Weeks.Journal of personalized medicine · 2023Article
- Laboratory markers to identify acute histological chorioamnionitis in febrile parturients undergoing epidural analgesia: a retrospective study.BMC pregnancy and childbirth · 2023Article
- Multi-modal MRI reveals changes in placental function following preterm premature rupture of membranes.Magnetic resonance in medicine · 2023Article
- Establishment of a prediction model for histological chorioamnionitis and its association with outcomes of premature infants.Frontiers in pediatrics · 2023Article
- Article
- Maternal β-hCG and Neutrophil Lymphocyte Ratio during Pregnancy to Predict High-Risk Neonates: an Observational Study.Maedica · 2022Article
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8 authors at 3 institutions in 1 country.
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Abstract
backgroundThe neutrophil-lymphocyte ratio (NLR) is easily calculated blood test parameter, which can be used as marker to predict many inflammatory disorders. The aim of this study was to assess and compare the NLR in maternal blood with the white blood cell (WBC) count and C-reactive protein (CRP) concentration for the prediction of histological chorioamnionitis.
methodsThis was a case-control study of 137 woman with preterm premature rupture of membranes (PPROM) at a gestational age between 22
resultsPatients with diagnosed histological chorioamnionitis (HCA) had significantly higher levels of WBC, CRP and NLR (p-value < 0.001). Levels of WBC, CRP and NLR predicted HCA with an area under the curve (AUC) of 0.81, 0.81 and 0.89, respectively. NLR had statistically significantly higher AUC than WBC, but no significant difference was found between AUCs of NLR and CRP. The cut-off level of NLR was found to be 5,97, which had a sensitivity of 77 % and a specificity of 95 %.
conclusionNLR has a good predictive value for HCA and could be used as an additional diagnostic marker for predicting histological chorioamnionitis in cases with preterm premature rupture of membranes before 34 weeks of gestation.
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