Evidence map›Paper›PMID 34579557›Full record

ArticleASN neuro

Astrocytic Hydrogen Sulfide Regulates Supraoptic Cellular Activity in the Adaptive Response of Lactating Rats to Chronic Social Stress.

Dongyang Li, Haitao Liu, Hongyang Wang, Shuwei Jia, Xiaoran Wang, Shuo Ling, Guichuan Chen, Xiaoyu Liu, Yu-Feng Wang

Open access · goldAbstract read
In one paragraph

Article in ASN neuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Intertwined associations between oxytocin, immune system and major depressive disorder.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Dongyang LiDepartment of Physiology, 12455Hainan Medical University, Haikou, China.ORCID 0000-0003-4159-7600
Haitao LiuDepartment of Physiology, School of Basic Medical Sciences, 34707Harbin Medical University, Harbin, China.
Hongyang WangDepartment of Physiology, School of Basic Medical Sciences, 34707Harbin Medical University, Harbin, China.
Shuwei JiaDepartment of Physiology, School of Basic Medical Sciences, 34707Harbin Medical University, Harbin, China.
Xiaoran WangDepartment of Physiology, School of Basic Medical Sciences, 34707Harbin Medical University, Harbin, China.
Shuo LingDepartment of Physiology, School of Basic Medical Sciences, 34707Harbin Medical University, Harbin, China.
Guichuan ChenDepartment of Physiology, School of Basic Medical Sciences, 34707Harbin Medical University, Harbin, China.
Xiaoyu LiuDepartment of Physiology, School of Basic Medical Sciences, 34707Harbin Medical University, Harbin, China.
Yu-Feng WangDepartment of Physiology, School of Basic Medical Sciences, 34707Harbin Medical University, Harbin, China.ORCID 0000-0001-8543-8906
Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maternal social stress among breastfeeding women can be adapted in chronic process. However, neuroendocrine mechanisms underlying such adaptation remain to be identified. Here, we report the effects of 2 hr/day unfamiliar male rat invasion (UMI) stress on maternal behaviors in lactating rats during postpartum day 8 (UMI8) to postpartum day 12 (UMI12). Rat dams at UMI8 presented signs of maternal anxiety, depression, and attacks toward male intruder. These changes partially reversed at UMI12 except the sign of anxiety. In the supraoptic nucleus (SON), UMI12 but not UMI8 significantly increased the expression of c-Fos and phosphorylated extracellular signal-regulated protein kinase 1/2. At UMI8 but not UMI12, length of glial fibrillary acidic protein (GFAP, astrocytic cytoskeletal element) filaments around oxytocin (OT) neurons was significantly longer than that of their controls; the amount of GFAP fragments at UMI12 was significantly less than that at UMI8. Expression of cystathionine β-synthase (CBS, enzyme for H

Indexed as

AstrocytesHydrogen SulfideAnimalsFemaleLactationMaleOxytocinRatsSupraoptic NucleusHydrogen SulfideOxytocinastrocyteglial fibrillary acidic proteinhydrogen sulfidelactationsocial stress

Identifiers

PMID34579557
PMCPMC8642056
OpenAlexW3203770711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.