Evidence map›Paper›PMID 34579548›Full record

ArticleNanomedicine (London, England)2021

Hyaluronic acid nanoparticle-encapsulated microRNA-125b repolarizes tumor-associated macrophages in pancreatic cancer.

Neha N Parayath, Brian V Hong, Gerardo G Mackenzie, Mansoor M Amiji

Open access · greenAbstract read
In one paragraph

Article in Nanomedicine (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Neha N ParayathDepartment of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0003-0860-1663
Brian V HongDepartment of Nutrition, University of California at Davis, Davis, CA 95616, USA.
Gerardo G MackenzieDepartment of Nutrition, University of California at Davis, Davis, CA 95616, USA.
Mansoor M AmijiDepartment of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0001-6170-881X
Northeastern University · USUniversity of California, Davis · US

Funding

Reprogramming Tumor-Associated Macrophages in PDAC with MicroRNA Nano-VectorsR21CA213114 · NCI · NORTHEASTERN UNIVERSITY · PI AMIJI, MANSOOR M., MACKENZIE, GERARDO GUILLERMO · 2017 to 2018
$388k
NCI NIH HHS R21 CA213114
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenocarcinomaMicroRNAsNanoparticlesPancreatic NeoplasmsTumor-Associated MacrophagesAnimalsHyaluronic AcidMiceTransfectionHyaluronic AcidMicroRNAsMirn125 microRNA, mousehyaluronic acid-poly(ethylene imine) nanoparticlesintraperitoneal administrationKPC micemicroRNA transfectionpancreatic adenocarcinomatumor-associated macrophages

Identifiers

PMID34579548
PMCPMC8493533
OpenAlexW3203542101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.