ArticleVaccines2021
Differential Effect of Vaccine Effectiveness and Safety on COVID-19 Vaccine Acceptance across Socioeconomic Groups in an International Sample.
Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Role of Trust in COVID-19 Vaccine Acceptance: Considerations from a Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Understanding the influence of religious and safety concerns on childhood measles and pertussis vaccination: a study conducted in Aceh, Indonesia, 2022.BMC infectious diseases · 2025Article
- Exploring healthcare workers' immunisation behaviour towards COVID-19 vaccines through psychological patterns.African journal of primary health care & family medicine · 2025Article
- A psychological insight of Moroccan adults' immunisation behaviour towards emergency vaccines.African journal of primary health care & family medicine · 2024Article
- COVID-19 vaccination preferences during a pause in Johnson & Johnson vaccine administration.Vaccine: X · 2023Article
- Antibody response, neutralizing potency, and transplacental antibody transfer following SARS-CoV-2 infection versus mRNA-1273, BNT162b2 COVID-19 vaccination in pregnancy.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023Article
- Article
- From Conspiracy to Hesitancy: The Longitudinal Impact of COVID-19 Vaccine Conspiracy Theories on Perceived Vaccine Effectiveness.Vaccines · 2023Article
- A Discrete Choice Analysis Comparing COVID-19 Vaccination Decisions for Children and Adults.JAMA network open · 2023Article
- Understanding Factors Influencing Polio Vaccine Uptake in Ghana-Developing Meaningful Community Mobilization and Engagement Strategies in Collaboration with Religious Leaders.The American journal of tropical medicine and hygiene · 2022Article
- Willingness-to-pay for a booster dose of inactivated SARS-CoV-2 vaccine in Taizhou, China.Human vaccines & immunotherapeutics · 2022Article
- Article
- Article
- Percentages of Vaccination Coverage Required to Establish Herd Immunity against SARS-CoV-2.Vaccines · 2022Article
- Individual Preferences for COVID-19 Vaccination under the China's 2021 National Vaccination Policy: A Discrete Choice Experiment Study.Vaccines · 2022Article
- Article
- Using a health belief model to assess COVID-19 vaccine intention and hesitancy in Jakarta, Indonesia.PLOS global public health · 2022Article
- Chinese University Students' Awareness and Acceptance of the COVID-19 Vaccine: A Cross-Sectional Study.Risk management and healthcare policy · 2022Article
- Mediators of Racial Differences in COVID-19 Vaccine Acceptance and Uptake: A Cohort Study in Detroit, MI.Vaccines · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Controlling the spread of SARS-CoV-2 will require high vaccination coverage, but acceptance of the vaccine could be impacted by perceptions of vaccine safety and effectiveness. The aim of this study was to characterize how vaccine safety and effectiveness impact acceptance of a vaccine, and whether this impact varied over time or across socioeconomic and demographic groups. Repeated cross-sectional surveys of an opt-in internet sample were conducted in 2020 in the US, mainland China, Taiwan, Malaysia, Indonesia, and India. Individuals were randomized into receiving information about a hypothetical COVID-19 vaccine with different safety and effectiveness profiles (risk of fever 5% vs. 20% and vaccine effectiveness 50% vs. 95%). We examined the effect of the vaccine profile on vaccine acceptance in a logistic regression model, and included interaction terms between vaccine profile and socioeconomic/demographic variables to examine the differences in sensitivity to the vaccine profile. In total, 12,915 participants were enrolled in the six-country study, including the US (4054), China (2797), Taiwan (1278), Malaysia (1497), Indonesia (1527), and India (1762). Across time and countries, respondents had stronger preferences for a safer and more effective vaccine. For example, in the US in November 2020, acceptance was 3.10 times higher for a 95% effective vaccine with a 5% risk of fever, vs a vaccine 50% effective, with a 20% risk of fever (95% CI: 2.07, 4.63). Across all countries, there was an increase in the effect of the vaccine profile over time (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.