Evidence map›Paper›PMID 34579182›Full record

ArticleVaccines2021

TB and SIV Coinfection; a Model for Evaluating Vaccine Strategies against TB Reactivation in Asian Origin Cynomolgus Macaques: A Pilot Study Using BCG Vaccination.

Andrew D White, Laura Sibley, Jennie Gullick, Charlotte Sarfas, Simon Clark, Zahra Fagrouch, Ernst Verschoor, Francisco J Salguero, Mike Dennis, Sally Sharpe

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Vaccines · 2024
    Article
  3. bioRxiv : the preprint server for biology · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Andrew D WhitePublic Health England, National Infections Service, Porton Down, Salisbury SP4 0JG, UK.ORCID 0000-0001-9481-0079
Laura SibleyPublic Health England, National Infections Service, Porton Down, Salisbury SP4 0JG, UK.
Jennie GullickPublic Health England, National Infections Service, Porton Down, Salisbury SP4 0JG, UK.
Charlotte SarfasPublic Health England, National Infections Service, Porton Down, Salisbury SP4 0JG, UK.ORCID 0000-0001-9056-0308
Simon ClarkPublic Health England, National Infections Service, Porton Down, Salisbury SP4 0JG, UK.
Zahra FagrouchDepartment of Virology, Biomedical Primate Research Centre, Lange Kleiweg 161, 2288 GJ Rijswijk, The Netherlands.
Ernst VerschoorDepartment of Virology, Biomedical Primate Research Centre, Lange Kleiweg 161, 2288 GJ Rijswijk, The Netherlands.ORCID 0000-0003-0912-2074
Francisco J SalgueroPublic Health England, National Infections Service, Porton Down, Salisbury SP4 0JG, UK.ORCID 0000-0002-5315-3882
Mike DennisPublic Health England, National Infections Service, Porton Down, Salisbury SP4 0JG, UK.
Sally SharpePublic Health England, National Infections Service, Porton Down, Salisbury SP4 0JG, UK.ORCID 0000-0002-7014-7660
Public Health England · GBBiomedical Primate Research Centre · NL

Funding

Seventh Framework Programme 11/0105
6 · The paper itself

Abstract

This pilot study aimed to determine the utility of a cynomolgus macaque model of coinfection with simian immunodeficiency virus (SIV) for the assessment of vaccines designed to prevent reactivation of TB. Following infection caused by aerosol exposure to an ultralow dose of

Indexed as

coinfectionmacaquesreactivationSIVtuberculosis

Identifiers

PMID34579182
PMCPMC8473354
OpenAlexW3195653583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.