Ghee Butter from Bovine Colostrum Reduces Inflammation in the Mouse Model of Acute Pancreatitis with Potential Involvement of Free Fatty Acid Receptors.

Aleksandra Tarasiuk, Marcin Talar, Kamila Bulak, Jakub Fichna

Open access · goldAbstract read

In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.6field-weighted citation impact, top 31% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Aleksandra TarasiukDepartment of Biochemistry, Faculty of Medicine, Medical University of Lodz, 92-215 Lodz, Poland.ORCID 0000-0002-5306-3158

Marcin TalarDepartment of Biochemistry, Faculty of Medicine, Medical University of Lodz, 92-215 Lodz, Poland.ORCID 0000-0001-8685-1161

Kamila BulakDepartment of Pathomorphology and Forensic Veterinary Medicine, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20-612 Lublin, Poland.

Jakub FichnaDepartment of Biochemistry, Faculty of Medicine, Medical University of Lodz, 92-215 Lodz, Poland.ORCID 0000-0002-8443-4417

Medical University of Lodz · PLUniversity of Life Sciences in Lublin · PL

Funding

Fundacja na rzecz Nauki Polskiej #503/1-156-04/503-11-001-19-00Uniwersytet Medyczny w Lodzi #503/1-156-04/503-11-001-19-00

6 · The paper itself

Abstract

Acute pancreatitis (AP) is an inflammatory disease that causes severe tissue damage. Ghee butter from bovine colostrum (GBBC) is a clarified butter produced by heating milk fat to 40 °C and separating the precipitating protein. As colostrum mainly contains fatty acids (FAs), immunoglobulins, maternal immune cells, and cytokines, we hypothesized that it may exert anti-inflammatory effects. We investigated the effects of GBBC on experimental AP in mice. Two intraperitoneal (

Indexed as

AmylasesAnimalsAnti-Inflammatory AgentsArginineCattleColostrumCytokinesDisease Models, AnimalFatty Acids, NonesterifiedFemaleGheeInflammationLipaseLungMaleMiceAmylasesAnti-Inflammatory AgentsArginineCytokinesFatty Acids, NonesterifiedFfar1 protein, mouseGheeLipasePeroxidaseReceptors, G-Protein-Coupledacute pancreatitiscolostrumghee butter from colostruminflammationL-arginine-induced acute pancreatitis

Identifiers

PMID34579147

DOI10.3390/nu13093271

PMCPMC8468552

OpenAlexW3199214729

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.