Evidence map›Paper›PMID 34579142›Full record

Trial reportNutrients2021

Effect of the Lifestyle, Exercise, and Nutrition (LEAN) Study on Long-Term Weight Loss Maintenance in Women with Breast Cancer.

Alexa Lisevick, Brenda Cartmel, Maura Harrigan, Fangyong Li, Tara Sanft, Miklos Fogarasi, Melinda L Irwin, Leah M Ferrucci

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Weight loss following nutritional education session among newly diagnosed breast cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexa LisevickFrank H. Netter MD School of Medicine, Quinnipiac University, Hamden, CT 06518, USA.ORCID 0000-0003-3790-4807
Brenda CartmelYale School of Public Health, Yale University, New Haven, CT 06510, USA.
Maura HarriganYale School of Public Health, Yale University, New Haven, CT 06510, USA.
Fangyong LiYale School of Public Health, Yale University, New Haven, CT 06510, USA.
Tara SanftYale Cancer Center, New Haven, CT 06510, USA.
Miklos FogarasiFrank H. Netter MD School of Medicine, Quinnipiac University, Hamden, CT 06518, USA.
Melinda L IrwinYale School of Public Health, Yale University, New Haven, CT 06510, USA.
Leah M FerrucciYale School of Public Health, Yale University, New Haven, CT 06510, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Pathology Tissue Services Shared ResourceP30CA016359 · NCI · YALE UNIVERSITY · PI Eric P. Winer · 1985 to 2026
$85.0M
Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
Transdisciplinary Research in Energetics and Cancer (TREC) Training GrantR25CA203650 · NCI · YALE UNIVERSITY · PI IRWIN, MELINDA L · 2016 to 2025
$2.9M
American Institute for Cancer Research N/ABreast Cancer Research Foundation N/ANCATS NIH HHS UL1 TR000142NCATS NIH HHS UL1 TR001863NCI NIH HHS P30 CA016359NCI NIH HHS R25 CA203650
6 · The paper itself

Abstract

Lifestyle interventions among breast cancer survivors with obesity have demonstrated successful short-term weight loss, but data on long-term weight maintenance are limited. We evaluated long-term weight loss maintenance in 100 breast cancer survivors with overweight/obesity in the efficacious six-month Lifestyle, Exercise, and Nutrition (LEAN) Study (intervention = 67; usual care = 33). Measured baseline and six-month weights were available for 92 women. Long-term weight data were obtained from electronic health records. We assessed weight trajectories between study completion (2012-2013) and July 2019 using growth curve analyses. Over up to eight years (mean = 5.9, SD = 1.9) of post-intervention follow-up, both the intervention (

Indexed as

ExerciseLife StyleNutritional StatusWeight LossAgedBreast NeoplasmsFemaleHumansMiddle AgedObesitySurvival Ratebreast cancerlifestyle interventionsurvivorshipweight loss maintenance

Identifiers

PMID34579142
PMCPMC8469752

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.