Evidence map›Paper›PMID 34579126›Full record

ArticleNutrients2021

Chitin Glucan Shifts Luminal and Mucosal Microbial Communities, Improve Epithelial Barrier and Modulates Cytokine Production In Vitro.

Marta Calatayud, Lynn Verstrepen, Jonas Ghyselinck, Pieter Van den Abbeele, Massimo Marzorati, Salvatore Modica, Thibaut Ranjanoro, Véronique Maquet

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Gut microbiota profiling of Javan pangolin (Manis javanica).The Journal of veterinary medical science · 2026
    Article
  3. Article
  4. Frontiers in nutrition · 2025
    Article
  5. A Synbiotic Combining Chitin-Glucan andInternational journal of molecular sciences · 2024
    Article
  6. Efficacy and tolerability of chitin-glucan combined with simethicone (GASTRAPWorld journal of gastrointestinal pharmacology and therapeutics · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Optimization of growth ofFrontiers in bioengineering and biotechnology · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Marta CalatayudProDigest BV, Technologiepark 82, 9052 Ghent, Belgium.ORCID 0000-0003-3592-3377
Lynn VerstrepenProDigest BV, Technologiepark 82, 9052 Ghent, Belgium.
Jonas GhyselinckProDigest BV, Technologiepark 82, 9052 Ghent, Belgium.
Pieter Van den AbbeeleProDigest BV, Technologiepark 82, 9052 Ghent, Belgium.
Massimo MarzoratiProDigest BV, Technologiepark 82, 9052 Ghent, Belgium.
Salvatore ModicaKitoZyme SA., Parc Industriel des Hauts Sarts, 4040 Herstal, Belgium.
Thibaut RanjanoroKitoZyme SA., Parc Industriel des Hauts Sarts, 4040 Herstal, Belgium.
Véronique MaquetKitoZyme SA., Parc Industriel des Hauts Sarts, 4040 Herstal, Belgium.
KitoZyme (Belgium) · BEProDigest (Belgium) · BEGhent University · BE

Funding

Gouvernement Wallon ADIPOSTOP project, convention 7366
6 · The paper itself

Abstract

The human gut microbiota has been linked to the health status of the host. Modulation of human gut microbiota through pro- and prebiotic interventions has yielded promising results; however, the effect of novel prebiotics, such as chitin-glucan, on gut microbiota-host interplay is still not fully characterized. We assessed the effect of chitin-glucan (CG) and chitin-glucan plus

Indexed as

Bifidobacterium breveCaco-2 CellsChitinCoculture TechniquesCytokinesEnterocytesFatty Acids, VolatileFecesFermentationGastrointestinal MicrobiomeGlucansHumansIntestinal MucosaPrebioticsProbioticsTHP-1 CellsChitinCytokinesFatty Acids, VolatileGlucansPrebioticschitin–glucangut microbiomeimmunomodulationintestinal barrierprebiotic

Identifiers

PMID34579126
PMCPMC8467507
OpenAlexW3199330898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.