Evidence map›Paper›PMID 34579118›Full record

ArticleNutrients2021

Adzuki Bean Alleviates Obesity and Insulin Resistance Induced by a High-Fat Diet and Modulates Gut Microbiota in Mice.

Qingyu Zhao, Dianzhi Hou, Yongxia Fu, Yong Xue, Xiao Guan, Qun Shen

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 111 citations in OpenAlex.

  1. Article
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  6. Needle extracts ofFrontiers in pharmacology · 2026
    Article
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  12. Article
  13. Using Gut Microbiota Modulation as a Precision Strategy Against Obesity.International journal of molecular sciences · 2025
    Review
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  15. Article
  16. Article
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  19. Regulation mechanism ofFrontiers in nutrition · 2025
    Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qingyu ZhaoCollege of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Dianzhi HouCollege of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Yongxia FuCollege of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Yong XueCollege of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.ORCID 0000-0002-6376-5006
Xiao GuanSchool of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.
Qun ShenCollege of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.ORCID 0000-0002-2154-6104
Nanjing Institute of Vegetable Science · CNUniversity of Shanghai for Science and Technology · CN

Funding

Cooperation project between China Agricultural University and Datong CityNational Key Research and Development Program of China 2017YFD0401202
6 · The paper itself

Abstract

Adzuki bean consumption has many health benefits, but its effects on obesity and regulating gut microbiota imbalances induced by a high-fat diet (HFD) have not been thoroughly studied. Mice were fed a low-fat diet, a HFD, and a HFD supplemented with 15% adzuki bean (HFD-AB) for 12 weeks. Adzuki bean supplementation significantly reduced obesity, lipid accumulation, and serum lipid and lipopolysaccharide (LPS) levels induced by HFD. It also mitigated liver function damage and hepatic steatosis. In particular, adzuki bean supplementation improved glucose homeostasis by increasing insulin sensitivity. In addition, it significantly reversed HFD-induced gut microbiota imbalances. Adzuki bean significantly reduced the ratio of

Indexed as

Insulin ResistanceVignaAnimal FeedAnimalsDiet, High-FatGastrointestinal MicrobiomeMaleMiceMice, Inbred C57BLObesityRandom Allocationadzuki beangut microbiotainsulin resistanceobesityPICRUSt2 analysis

Identifiers

PMID34579118
PMCPMC8466346
OpenAlexW3199461112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.